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The Vascular Impairment of Cognition Classification Consensus Study.

Journal article
Authors Olivia A Skrobot
John O'Brien
Sandra Black
Christopher Chen
Charles DeCarli
Timo Erkinjuntti
Gary A Ford
Rajesh N Kalaria
Leonardo Pantoni
Florence Pasquier
Gustavo C Roman
Anders Wallin
Perminder Sachdev
Ingmar Skoog
Yoav Ben-Shlomo
Anthony P Passmore
Seth Love
Patrick G Kehoe
Published in Alzheimer's & dementia : the journal of the Alzheimer's Association
Volume 13
Issue 6
Pages 624-33
ISSN 1552-5279
Publication year 2017
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Centre for Ageing and Health (Agecap)
Pages 624-33
Language en
Subject categories Neuroscience


Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment.The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines.VICCCS had a mean of 122 (98-153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge.VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research.

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