To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Accumulation of CCR4 CTLA… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Accumulation of CCR4 CTLA-4 FOXP3CD25 Regulatory T Cells in Colon Adenocarcinomas Correlate to Reduced Activation of Conventional T Cells.

Journal article
Authors Helena Svensson
Veronica Olofsson
Samuel B Lundin
Chakradhar Yakkala
Stellan Björck
Lars Börjesson
Bengt Gustavsson
Marianne Quiding-Järbrink
Published in PloS one
Volume 7
Issue 2
Pages article number e30695
ISSN 1932-6203
Publication year 2012
Published at Institute of Clinical Sciences, Department of Surgery
Institute of Biomedicine, Department of Microbiology and Immunology
Pages article number e30695
Language en
Subject categories Surgery


Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for unknown reasons the resulting immunity is not able to clear the tumor. Recruitment of activated effector lymphocytes to the tumor is important for efficient anti-tumor responses, while the presence of regulatory T cells (Treg) down-modulate tumor-specific immunity. We therefore aimed to determine homing mechanisms and activation stage of Treg and effector T cell infiltrating colon tumors compared to cells from the unaffected mucosa in patients suffering from colon adenocarcinoma.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?

Denna text är utskriven från följande webbsida:
Utskriftsdatum: 2020-07-13