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Laparoscopic antireflux surgery vs esomeprazole treatment for chronic GERD: the LOTUS randomized clinical trial.

Journal article
Authors Jean-Paul Galmiche
Jan Hatlebakk
Stephen Attwood
Christian Ell
Roberto Fiocca
Stefan Eklund
Göran Långström
Tore Lind
Lars Lundell
Cecilia Engström
Published in JAMA : the journal of the American Medical Association
Volume 305
Issue 19
Pages 1969-77
ISSN 1538-3598
Publication year 2011
Published at Institute of Clinical Sciences, Department of Surgery
Pages 1969-77
Language en
Keywords Adult, Anti-Ulcer Agents, administration & dosage, adverse effects, Chronic Disease, Digestive System Surgical Procedures, adverse effects, methods, Female, Gastroesophageal Reflux, drug therapy, surgery, Humans, Laparoscopy, adverse effects, methods, Male, Middle Aged, Omeprazole, administration & dosage, adverse effects, Remission Induction, Severity of Illness Index, Treatment Outcome
Subject categories Surgery


Gastroesophageal reflux disease (GERD) is a chronic, relapsing disease with symptoms that have negative effects on daily life. Two treatment options are long-term medication or surgery.

Page Manager: Webmaster|Last update: 9/11/2012

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