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Osteoporosis in adults with meningomyelocele: an unrecognized problem at rehabilitation clinics.

Review article
Authors Kirsi Valtonen
Lars-Åke Goksör
Olof Jonsson
Dan Mellström
Hannu Alaranta
Eira Viikari-Juntura
Published in Arch Phys Med Rehabil
Volume 87
Issue 3
Pages 376-382
Publication year 2006
Published at Institute of Medicine, School of Public Health and Community Medicine
Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Institute of Clinical Sciences
Pages 376-382
Language en
Keywords Bone density; Meningomyelocele; Osteoporosis; Rehabilitation
Subject categories Endocrinology, Urology and andrology


Abstract Valtonen KM, Goksör L-Å, Jonsson O, Mellström D, Alaranta HT, Viikari-Juntura ER. Osteoporosis in adults with meningomyelocele: an unrecognized problem at rehabilitation clinics. Objectives To assess the prevalence of osteoporosis and osteopenia in adults with meningomyelocele and to explore whether neurologic level, ambulatory status, and other medical problems are associated with bone mineral density (BMD). Design A cross-sectional study, including a self-administered questionnaire and clinical assessment. Setting Outpatient referral clinic in Sweden. Participants Twenty-one adults (mean age, 30y) with meningomyelocele admitted to the Young Adult Teams in Göteborg and Bo̊ras, Sweden. Interventions Not applicable. Main Outcome Measures BMD in the lumbar spine and hip and forearm measured with dual x-ray absorptiometry. Results Seven (33%) subjects had osteoporosis in at least 1 of the measured sites. Three patients had osteopenia and 2 had osteoporosis in the lumbar spine. Among the 15 subjects whose BMD of the hip region could be reliably measured, 7 (47%) had osteoporosis in the femoral neck or trochanteric region of the hip. Subjects with other medical problems commonly occurring in meningomyelocele had lower BMD in the femoral neck and trochanteric region of the hip than subjects without such factors. Ambulation alone showed only a tendency to be associated with BMD of the femoral neck, whereas the effect of other medical risk factors on BMD of the femoral neck was stronger among the nonambulators than the ambulators. Conclusions Our results show that osteoporosis is a medical problem to be considered when treating and rehabilitating patients with meningomyelocele.

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