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Triphasic and quadriphasic waveforms are superior to biphasic waveforms for synchronized beating of cardiomyocytes.

Journal article
Authors Lars Enochson
Joakim Sandstedt
Hans Strandberg
Cecilia Emanuelsson
Andreas Ornberg
Anders Lindahl
Camilla Karlsson
Published in Journal of electrocardiology
Volume 45
Issue 3
Pages 305-11
ISSN 1532-8430
Publication year 2012
Published at Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine
Institute of Clinical Sciences, Department of Biomaterials
Pages 305-11
Language en
Keywords Action Potentials, physiology, Animals, Biological Clocks, physiology, Cardiac Pacing, Artificial, methods, Cell Line, Electrodes, Mice, Myocytes, Cardiac, physiology, Pacemaker, Artificial
Subject categories Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy)


Within pacemaker research few attempts have been made to find an optimal waveform phase sequence that synchronizes beating of cardiomyocytes at an electrode. Multielectrode arrays (MEAs) offer electrophysiological screening of cardiomyocytes serving as a system for preliminary screening of pacing waveform design.

Page Manager: Webmaster|Last update: 9/11/2012

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