To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Functional subdivision of… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Functional subdivision of feline spinal interneurons in reflex pathways from group Ib and II muscle afferents; an update.

Journal article
Authors Elzbieta Jankowska
Steve A Edgley
Published in The European journal of neuroscience
Volume 32
Issue 6
Pages 881-93
ISSN 1460-9568
Publication year 2010
Published at Institute of Neuroscience and Physiology, Department of Physiology
Pages 881-93
Language en
Keywords Afferent Pathways, physiology, Animals, Cats, Humans, Interneurons, physiology, Muscle Contraction, physiology, Muscle, Skeletal, physiology, Nerve Net, physiology, Reflex, Stretch, physiology, Spinal Nerves, physiology
Subject categories Neurophysiology


A first step towards understanding the operation of a neural network is identification of the populations of neurons that contribute to it. Our aim here is to reassess the basis for subdivision of adult mammalian spinal interneurons that mediate reflex actions from tendon organs (group Ib afferents) and muscle spindle secondary endings (group II afferents) into separate populations. Re-examining the existing experimental data, we find no compelling reasons to consider intermediate zone interneurons with input from group Ib afferents to be distinct from those co-excited by group II afferents. Similar patterns of distributed input have been found in subpopulations that project ipsilaterally, contralaterally or bilaterally, and in both excitatory and inhibitory interneurons; differences in input from group I and II afferents to individual interneurons showed intra- rather than inter-population variation. Patterns of reflex actions evoked from group Ib and II afferents and task-dependent changes in these actions, e.g. during locomotion, may likewise be compatible with mediation by premotor interneurons integrating information from both group I and II afferents. Pathological changes after injuries of the central nervous system in humans and the lineage of different subclasses of embryonic interneurons may therefore be analyzed without need to consider subdivision of adult intermediate zone interneurons into subpopulations with group Ib or group II input. We propose renaming these neurons 'group I/II interneurons'.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?