To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Perinatal complications i… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Perinatal complications in patients with unisutural craniosynostosis: An international multicentre retrospective cohort study

Journal article
Authors M. J. Cornelissen
Madiha Bhatti Söfteland
I. Apon
Lars Ladfors
I. M. J. Mathijssen
T. E. Cohen-Overbeek
G. J. Bonsel
Lars Kölby
Published in Journal of Cranio-Maxillofacial Surgery
Volume 45
Issue 11
Pages 1809-1814
ISSN 1010-5182
Publication year 2017
Published at Institute of Clinical Sciences, Department of Plastic Surgery
Institute of Clinical Sciences, Department of Obstetrics and Gynecology
Pages 1809-1814
Language en
Keywords Craniosynostosis, Perinatal complications, Caesarean section, Etiology, postterm pregnancy, prevalence, stage, fetal
Subject categories Surgery, Obstetrics, Gynecology and Reproductive Medicine


Purpose: Craniosynostosis may lead to hampered fetal head molding and birth complications. To study the interaction between single suture craniosynostosis and delivery complications, an international, multicentre, retrospective cohort study was performed. Materials and methods: All infants born between 2006 and 2012 in the Netherlands and Sweden with sagittal or metopic suture synostosis were included. All births were included as a reference population. The primary outcome measure was rate of medically assisted labor. The secondary outcomes included method of conception, term of birth and fetal position. Results: We included 152 trigonocephaly patients, 272 scaphocephaly patients and 1.954.141 controls. A higher rate of assisted reproductive technology (ART) was found in patients with trigonocephaly (13%) and scaphocephaly (7%) compared to controls (3%, p < 0.001). Scaphocephaly resulted in more postterm births (8% vs 4%, p < 0.001). Trigonocephaly patients showed more preterm births (11% vs 6%, p < 0.001), breech position was more frequent (10% vs 4%, p = 0.003) and labor was more often induced. Rate of assisted delivery, including cesarean section, was significantly higher in both patient groups. Conclusions: Scaphocephaly leads to more postterm births and an increased rate of cesarean sections. Trigonocephaly is related to ART, and in addition higher rates of breech position and cesarean section are found. Prenatal detection of single suture craniosynostosis could improve perinatal care. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?