To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

A multifaceted 'omics' ap… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

Contact form








 


Note! If you want an answer on a question you must specify your email address




A multifaceted 'omics' approach for addressing the challenge of antimicrobial resistance

Journal article
Authors A. Cohen
L. Bont
D. Engelhard
Edward R.B. Moore
D. Fernandez
R. Kreisberg-Greenblatt
K. Oved
E. Eden
J. P. Hays
Published in Future Microbiology
Volume 10
Issue 3
Pages 365-376
ISSN 1746-0913
Publication year 2015
Published at Institute of Biomedicine
Pages 365-376
Language en
Links dx.doi.org/10.2217/fmb.14.127
Keywords antibiotic resistance, bioinformatics, genomics, mass spectrometry, microbiota, proteomics, COMMUNITY-ACQUIRED PNEUMONIA, GENOME-WIDE ASSOCIATION, CHRONIC, HEPATITIS-C, INFECTIOUS-DISEASE, ABACAVIR HYPERSENSITIVITY, GENETIC-VARIATION, HUMAN MICROBIOME, HEALTH, HLA-B-ASTERISK-5701, ANTIBIOTICS, Microbiology
Subject categories Clinical Medicine

Abstract

The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagnostic solutions. A multifaceted 'omics' approach that integrates personalized patient data such as genetic predisposition to infections (genomics), natural microbiota composition and immune response to infection (proteomics and transcriptomics) together with comprehensive pathogen profiling has the potential to help physicians improve their antimicrobial prescribing practices. In this respect, the EU has funded a multidisciplinary project (TAILORED-Treatment) that will develop novel omics-based personalized treatment schemes that have the potential to reduce antibiotic consumption, and help limiting the spread of antibiotic resistance.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?