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Infection of infants with human herpesvirus type 6 may be associated with reduced allergic sensitization and T-helper type 2 development.

Journal article
Authors Inger Nordström
Anna Rudin
Ingegerd Adlerberth
Agnes E Wold
Robert Saalman
Bill Hesselmar
Nils Åberg
Jan-Åke Liljeqvist
Kristina Eriksson
Published in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Volume 40
Issue 6
Pages 882-90
ISSN 1365-2222
Publication year 2010
Published at Institute of Medicine, Department of Rheumatology and Inflammation Research
Institute of Clinical Sciences, Department of Pediatrics
Institute of Biomedicine, Department of Infectious Medicine
Pages 882-90
Language en
Links dx.doi.org/10.1111/j.1365-2222.2010...
Keywords Allergens, immunology, Cytokines, metabolism, Down-Regulation, Enzyme-Linked Immunosorbent Assay, Female, Flow Cytometry, Herpesvirus 6, Human, immunology, pathogenicity, Humans, Hypersensitivity, immunology, Immunoglobulin E, blood, Infant, Interferon-alpha, immunology, metabolism, Male, Roseolovirus Infections, immunology, virology, Th2 Cells, immunology
Subject categories Microbiology in the medical area

Abstract

Epidemiological studies point to an inverse relationship between microbial exposure and the prevalence of allergic diseases. The underlying mechanism for this observation remains largely unknown, as well as the nature of the microbes involved.

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