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- Sören Riis Paludan
Sören Riis Paludan
Researcher
Department of Rheumatology and Inflammation-
ER stress induces caspase-2-tBID-GSDMEdependent cell death in neurons lytically infected with herpes simplex virus type
2
Fanghui Ren, Ryo Narita, Ahmad S. Rashidi, Stefanie Fruhwürth, Zongliang Gao, Rasmus O. Bak, Martin K. Thomsen, Georges M. G. M. Verjans, Line S. Reinert, Sören R Paludan
EMBO JOURNAL - 2023 -
An IKBKE variant conferring functional cGAS/STING pathway deficiency and susceptibility to recurrent HSV-2
meningitis.
Azadeh Reyahi, Marie Studahl, Morten K Skouboe, Stefanie Fruhwürth, Ryo Narita, Fanghui Ren, Moa Bjerhem Viklund, Marie B Iversen, Mette Christiansen, Alexandra Svensson, Trine H Mogensen, Kristina Eriksson, Sören R Paludan
JCI insight - 2023 -
TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the
brain
Stefanie Fruhwürth, L. S. Reinert, Carl Öberg, Marcelina Sakr, M. Henricsson, Henrik Zetterberg, Sören R Paludan
Science Advances - 2023 -
The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from
COVID-19.
Viktoria Hennings, Karolina Thörn, Sofie Albinsson, Christine Lingblom, Kerstin Andersson, Christer Andersson, Katarina Järbur, Rille Pullerits, Manja Idorn, Sören R Paludan, Kristina Eriksson, Christine Wennerås
European journal of immunology - 2022 -
Constitutive and latent immune mechanisms exert 'silent' control of virus infections in the central nervous
system
Sören R Paludan, T. H. Mogensen
Current Opinion in Immunology - 2021 -
Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical
Neurons
Petra Bergström, Edward Trybala, Charlotta Eriksson, Maria Johansson, Tugce Munise Satir, Sibylle Widehn, Stefanie Fruhwürth, W. Michno, Faisal Hayat Nazir, Jörg Hanrieder, Sören R Paludan, Lotta Agholme, Henrik Zetterberg, Tomas Bergström
Viruses-Basel - 2021 -
Constitutive immune mechanisms: mediators of host defence and immune
regulation
Sören R Paludan, T. Pradeu, S. L. Masters, T. H. Mogensen
Nature Reviews Immunology - 2021 -
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in
humans
A. S. Hait, D. Olagnier, V. Sancho-Shimizu, K. A. Skipper, M. Helleberg, S. M. Larsen, C. Bodda, L. I. Moldovan, F. H. Ren, N. S. B. Andersen, M. M. Thomsen, M. R. Freytag, S. Darmalinggam, I. Parkes, D. D. Kadekar, S. H. Rahbek, D. van der Horst, L. S. Kristensen, Kristina Eriksson, J. Kjems, S. Mostowy, M. Christiansen, J. G. Mikkelsen, C. T. Brandt, Sören R Paludan, T. H. Mogensen
Science Immunology - 2020 -
HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain
infection
C. Bodda, L. S. Reinert, Stefanie Fruhwürth, T. Richardo, C. Sun, B. C. Zhang, M. Kalamvoki, A. Pohlmann, T. H. Mogensen, Petra Bergström, Lotta Agholme, P. O'Hare, B. Sodeik, M. Gyrd-Hansen, Henrik Zetterberg, Sören R Paludan
The Journal of experimental medicine - 2020 -
HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein
ICP0
N. Hensel, V. Raker, B. Forthmann, N. T. Detering, S. Kubinski, A. Buch, G. Katzilieris-Petras, J. Spanier, V. Gudi, S. Wagenknecht, V. Kopfnagel, T. A. Werfel, M. Stangel, A. Beineke, U. Kalinke, Sören R Paludan, B. Sodeik, P. Claus
Journal of Neuroinflammation - 2019 -
DNA-stimulated cell death: implications for host defence, inflammatory diseases and
cancer
Sören R Paludan, L. S. Reinert, V. Hornung
Nature Reviews Immunology - 2019 -
RNA Polymerase III as a Gatekeeper to Prevent Severe VZV
Infections
M. E. Carter-Timofte, Sören R Paludan, T. H. Mogensen
Trends in Molecular Medicine - 2018