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Astrid von Mentzer - University of Gothenburg, Sweden Till startsida
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Astrid von Mentzer

Postdoctor

Astrid von Mentzer
Postdoctor
astrid.von.mentzer@gu.se

Visiting Address: Chalmers tvärgata 3 , 41296 Göteborg


Applied Mathematics and Statistics at Department of Mathematical Sciences (More Information)
412 96 Göteborg
Visiting Address: Chalmers Tvärgata 3 , 412 96 Göteborg

About Astrid von Mentzer

Enterotoxigenic Escherichia coli (ETEC) is a bacterial pathogen which causes diarrheal illness in low-income countries lacking access to clean water and fundamental sanitation. ETEC is one of the major causes of diarrhea in developing countries and, consequently deaths among both children and adults.

My research project involves both genomic analyses and experimental methods to study this highly variable pathogen. Using genomics I study the population structure of ETEC and investigate how pathogenic ETEC strains may arise and are spread. In addition, using sequencing I investigate both known and novel virulence factors, mainly proteins involved in attachment of the bacteria to the human intestine, which can be used as a basis for future vaccine research. Two approaches to identify and characterize novel adhesive proteins using both genomics and experimental methods as been developed.

Latest publications

An untypeable enterotoxigenic Escherichia coli represents one of the dominant types causing human disease
Atsushi Iguchi, Astrid von Mentzer, Taisei Kikuchi, Nicholas R. Thomson
Microbial Genomics, Journal article 2017
Journal article

Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.
Paulina Akeus, Veronica Langenes, Jonas Kristensen, Astrid von Mentzer, Tim Sparwasser et al.
European journal of immunology, Journal article 2015
Journal article

Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization Factors
Enrique Joffre, Astrid von Mentzer, M. Abd El Ghany, N. Oezguen, T. Savidge et al.
Journal of Bacteriology, Journal article 2015
Journal article

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution
Astrid von Mentzer, T. R. Connor, L. H. Wieler, T. Semmler, A. Iguchi et al.
Nature Genetics, Journal article 2014
Journal article

Showing 1 - 10 of 12

2018

2017

An untypeable enterotoxigenic Escherichia coli represents one of the dominant types causing human disease
Atsushi Iguchi, Astrid von Mentzer, Taisei Kikuchi, Nicholas R. Thomson
Microbial Genomics, Journal article 2017
Journal article

2016

2015

Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.
Paulina Akeus, Veronica Langenes, Jonas Kristensen, Astrid von Mentzer, Tim Sparwasser et al.
European journal of immunology, Journal article 2015
Journal article

Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization Factors
Enrique Joffre, Astrid von Mentzer, M. Abd El Ghany, N. Oezguen, T. Savidge et al.
Journal of Bacteriology, Journal article 2015
Journal article

2014

Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution
Astrid von Mentzer, T. R. Connor, L. H. Wieler, T. Semmler, A. Iguchi et al.
Nature Genetics, Journal article 2014
Journal article

Showing 1 - 10 of 12

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