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OPEN POSITIONS Doctoral student in Medical Science - Transplantation solutions for female infertility

Project title: Tissue engineering for novel female infertility treatments

Job assignments

Third-cycle studies are equivalent to four year full-time and lead to a Degree of Doctor. Those appointed to doctoral studentships shall primarily devote themselves to their studies. Those appointed to doctoral studentships may, however, work to a limited extent with educational tasks, research and administration. Before a PhD degree has been awarded, duties of this kind may not comprise more than 20 per cent of a full-time post.

The PhD education in Medical Science comprise carrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see https://medarbetarportalen.gu.se/sahlgrenskaakademin/forskarutbildning/languageId=100001

Project
Background: The successful candidate will work in the Swedish uterus transplantation (UTx) group’s pre-clinical research lab. So far, all babies born following a UTx at our center were from live-donor proceedings. This involves long and risky donor surgery. Moreover, all transplanted patients face the risk of tissue rejection and immunosuppressant-related side effects. The development of an alternative donor source, for example through the development of an engineered grafting material based on biological scaffolds and the patient’s own stem cells to reduce rejection complications and risky donor surgery would greatly benefit UTx patients.

Purpose/Aim: With animal models (rat, sheep and baboon) and novel tissue engineering strategies develop patient-specific tissue transplants suitable for the treatment of female infertility. Research focus will be on using decellularized organs that are recellularized with various stem cells. 3D-printing may also be evaluated as a potential strategy to develop such tissues.

Methods: This PhD project will require a lot of cell culturing, work with organ perfusion systems, animal surgery, digital PCR, gene therapy with lentiviral vectors and CRISPR/CAS9. The work require that the PhD candidate can work independently and disciplined towards a long-term goal, and along the way, be able to complete several targets that will lead into multiple publications in peer-reviewed scientific journals written in English.

Eligibility

To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements.

A person meets the general entry requirements for third-cycle studies if he or she:
1. has been awarded a second-cycle qualification
2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or
3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad

A person meets the specific entry requirements for third-cycle studies in Medical Science if he or she: has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies

Assessment

In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for:
- specific knowledge and skills within the subject area and related research fields
- experience of scientific theory and relevant research methodology
- scientific analysis and presentation verified through thesis, degree project, scientific journals or the like.

Documented experience of cell culture work (in particular with various stem cells) and molecular methods is of merit. Previous knowledge about various tissue engineering strategies is desirable, also lentiviral production and experience with the gene editing system CRISPR/CAS9. Apart from this, excellent ability to communicate in written and spoken English is advantageous. The successful applicant needs to fit-in the research team, be structured and organized. Personal attributes may be considered important.

Employment

After admission to third-cycle studies you will be appointed to doctoral studentship. Regulations for employment of doctoral students are given in SFS 1993:100. The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. A person may be appointed to a doctoral studentship for a total of eight years. The total employment period may, however, not exceed the time corresponding to full-time third-cycle study for four years.

Location: Sahlgrenska Academy, Institute of Clinical Sciences, Department of Obstetrics and Gynecology. Extent: 100%. First day of employment: as agreed.

Salaries for doctoral students are regulated in a local agreement at the University. 

For further information regarding the position

For more information about the project please contact:

Principal supervisor Mats Brännström, Professor, mats.brannstrom@obgyn.gu.se
Assistant supervisor Mats Hellström, Associate Professor, mats.hellstrom@gu.se

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

You must include the following, in pdf format

  • Personal letter
  • CV
  • Diploma and transcripts showing that you meet with the general entry requirement
  • Proof of completion of  English 6 course or the acquired equivalent knowledge through previous studies

If your degree is from a university outside of Sweden, check what you need to submit at https://www.universityadmissions.se/en/All-you-need-to-know1/Applying-for-studies/Documenting-your-eligibility-for-studies/Instructions-for-Masters-applicants/Specific-requirements-for-my-country1/ where you can also see what you need to submit in order to fulfill the English language requirement.

  • If your degree has not been verified by a Swedish authority you need to provide contact details to the issuing university, registrar or similar, that can verify the degree at our request.

Closing date: 2019-08-12 

 

The University of Gothenburg promotes equal opportunities, equality and diversity.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.

The University of Gothenburg tackles society’s challenges with diverse knowledge. 47 500 students and 6 400 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

Page Manager: rekrytering@gu.se|Last update: 2/23/2017
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