Advanced Functional Genomics
The course in Advanced Functional Genomics is aimed at you who is curious about how the new large-scale techniques for genome-wide analysis work and how they can contribute to a better understanding of the function of life's molecules. Integration of different types of experimental data is an important part of functional genomics where system biological models over cellular modules are central.
The course introduces the theoretical foundations of systems biology as well as large-scale experimental methodology.
- You will gain in-depth knowledge of how to experimentally perform large-scale analyses of transcripts (transcriptomics), proteins (proteomics), metabolites (metabolomics) and phenotypes (phenomics).
- You will learn the basics of systems biology by creating mathematical models of cellular modules such as signaling pathways and metabolic systems. Simulations are a natural part of the course to test and verify the model predictions.
- You will learn how to introduce genetic changes in different experimental model systems, which is central to being able to test given hypotheses about the function of genes.
The course contains elements that provide increased understanding and reflection on ethical aspects linked to the new technologies. Seminars and study visits are also included to provide greater insight into existing and future labour markets.
Great emphasis is placed on own seminars, report-writing and literature studies.
The teaching is based on traditional lectures that are interspersed with work in smaller groups. Several of the assignments during the course are clearly problem-based and result in written reports and oral presentations. This gives you a deeper knowledge and you become better at analysing and thinking scientifically about how new knowledge is generated and how it is best presented. Great emphasis is placed on training in writing scientific texts.
The course provides also a mixture of laboratory (wet-lab) work where you are introduced to automated/robotic techniques and computer-based analyses. You will also pay a study visit to a pharmaceutical company.
During the course, you will have close contact with dedicated teachers who research in the field, and also with international teachers.
The course is in English.