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University of Gothenburg

PhD Course: Bioinformatics II

The course contains a combination of lectures and practical sessions that introduce the analysis of DNA sequencing (variant analysis) and RNA sequencing (gene expression analysis). Total RNA and single cell RNA are covered.

Bioinformatics Figures
 Hours (HP):  54 (2,0)
 Code (s):  SC000XX
Week (s):  34-37 (38 examination)

The following topics covered are:

  • Use of programs to analyze the quality of DNA and RNA sequence data.
  • Mapping DNA and RNA sequence data against a reference genome.
  • Identify genetic variants in relation to a reference.
  • Compare gene expression for groups of different phenotype using RNA sequence data.
  • Analyze difference in gene expression, between different cell types using single-cell data.
  • Clustering and geneontology to analyze how changes in RNA expression can affect biological processes in the cell


The course comprises 54 working hours where you are expected to spend time of your own to complete the exercises (self-studies).

Participants are required to bring their own computer with the corresponding administrator rights.  

If you want to learn how to generate the results from this course, we recommend you to take the Analysis of next generation sequencing data course


Course Prerequisites

Bioinformatics I