Michal Maj
Postdoctoral Research Fellow
Department of Chemistry & MolecularAbout Michal Maj
Research in the Maj group focuses on studying the structure and aggregation kinetics of amyloid intermediates using laser spectroscopy and high-resolution imaging techniques. Many diseases are caused by aggregation of misfolded proteins into amyloid fibrils. We take advantage of the rapid acquisition of femtosecond two-dimensional infrared (2D-IR) spectroscopy to elucidate mechanisms of such protein self-assembly. To increase the structural specificity of 2D-IR, we develop new molecular probes that can be used as IR-active sensors of structure and dynamics of proteins.
For more information see https://www.majgroup.net
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Ultrafast structural changes within a photosynthetic reaction
centre.
Robert Dods, Petra Båth, Dmitry Morozov, Viktor Ahlberg Gagnér, David Arnlund, Hoi Ling Luk, Joachim Kübel, Michal Maj, Adams Vallejos, Cecilia Wickstrand, Robert Bosman, Kenneth R Beyerlein, Garrett Nelson, Mengning Liang, Despina Milathianaki, Joseph Robinson, Rajiv Harimoorthy, Peter Berntsen, Erik Malmerberg, Linda C Johansson, Rebecka Andersson, Sergio Carbajo, Elin Claesson, Chelsie E Conrad, Peter Dahl, Greger Hammarin, Mark S Hunter, Chufeng Li, Stella Lisova, Antoine Royant, Cecilia Safari, Amit Sharma, Garth J Williams, Oleksandr Yefanov, Sebastian Westenhoff, Jan Davidsson, Daniel P DePonte, Sébastien Boutet, Anton Barty, Gergely Katona, Gerrit Groenhof, Gisela Brändén, Richard Neutze
Nature - 2021-01-01 -
Transient IR spectroscopy identifies key interactions and unravels new intermediates in the photocycle of a bacterial
phytochrome
Joachim Kübel, Manoop Chenchiliyan, Saik Ann Ooi, Emil Gustavsson, Linnéa Isaksson, V. Kuznetsova, J. A. Ihalainen, Sebastian Westenhoff, Michal Maj
Physical chemistry chemical physics : PCCP - 2020-01-01 -
The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray
laser
Elin Claesson, Weixiao Yuan Wahlgren, H. Takala, S. Pandey, Leticia Castillon, V. Kuznetsova, Léocadie Henry, Matthijs R Panman, M. Carrillo, Joachim Kübel, R. Nanekar, Linnéa Isaksson, Amke Nimmrich, Andrea Cellini, D. Morozov, Michal Maj, M. Kurttila, Robert Bosman, E. Nango, R. Tanaka, T. Tanaka, L. Fangjia, S. Iwata, S. Owada, K. Moffat, G. Groenhof, E. A. Stojkovic, J. A. Ihalainen, M. Schmidt, Sebastian Westenhoff
eLife - 2020-01-01 -
Ultrafast Chemical Exchange Dynamics of Hydrogen Bonds Observed via Isonitrile Infrared Sensors: Implications for Biomolecular
Studies
Joachim Kübel, G. Lee, Saik Ann Ooi, Sebastian Westenhoff, H. Han, M. Cho, Michal Maj
Journal of Physical Chemistry Letters - 2019-01-01