Erik Portelius
-
Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure
hydrocephalus
Karolina Minta, Anna Jeppsson, Gunnar Brinkmalm, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Mats Tullberg, Ulf Andreasson
Fluids and Barriers of the CNS - 2021-01-01 -
Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer's
disease
H. V. Dansson, L. Stempfle, H. Egilsdottir, Alexander Schliep, Erik Portelius, Kaj Blennow, Henrik Zetterberg, F. D. Johansson
Alzheimers Research & Therapy - 2021-01-01 -
Population-based blood screening for preclinical Alzheimer's disease in a British birth cohort at age
70.
Ashvini Keshavan, Josef Pannee, Thomas Karikari, Juan Rodriguez, Nicholas J. Ashton, Jennifer M Nicholas, David M Cash, William Coath, Christopher A Lane, Thomas D Parker, Kirsty Lu, Sarah M Buchanan, Sarah E Keuss, Sarah-Naomi James, Heidi Murray-Smith, Andrew Wong, Anna Barnes, John C Dickson, Amanda Heslegrave, Erik Portelius, Marcus Richards, Nick C Fox, Henrik Zetterberg, Kaj Blennow, Jonathan M Schott
Brain : a journal of neurology - 2021-01-01 -
Characterization of monomeric and soluble aggregated Aβ in Down's syndrome and Alzheimer's disease
brains.
Eleni Gkanatsiou, Charlotte Sahlin, Erik Portelius, Malin Johannesson, Linda Söderberg, Johanna Fälting, Hans Basun, Christer Möller, Tomas Odergren, Henrik Zetterberg, Kaj Blennow, Lars Lannfeldt, Gunnar Brinkmalm
Neuroscience letters - 2021-01-01 -
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's
disease.
Diego Sepulveda-Falla, Lucia Chavez-Gutierrez, Erik Portelius, Jorge I Vélez, Simon Dujardin, Alvaro Barrera-Ocampo, Felix Dinkel, Christian Hagel, Berta Puig, Claudio Mastronardi, Francisco Lopera, Bradley T Hyman, Kaj Blennow, Mauricio Arcos-Burgos, Bart de Strooper, Markus Glatzel
Acta neuropathologica - 2021-01-01 -
Prediction of Outcome After Endovascular Embolectomy in Anterior Circulation Stroke Using
Biomarkers.
Fani Pujol-Calderón, Henrik Zetterberg, Erik Portelius, Pia Löwhagen Hendén, Alexandros Rentzos, Jan-Erik Karlsson, Kina Höglund, Kaj Blennow
Translational stroke research - 2021-01-01 -
Brevican and Neurocan Peptides as Potential Cerebrospinal Fluid Biomarkers for Differentiation Between Vascular Dementia and Alzheimer's
Disease.
Karolina Minta, Gunnar Brinkmalm, Erik Portelius, Per Johansson, Johan Svensson, Petronella Kettunen, Anders Wallin, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Journal of Alzheimer's disease : JAD - 2021-01-01 -
Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain
injury.
Karolina Minta, Gunnar Brinkmalm, Eric P Thelin, Faiez Al Nimer, Fredrik Piehl, Mats Tullberg, Anna Jeppsson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Clinica chimica acta; international journal of clinical chemistry - 2021-01-01 -
Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain
injury.
Karolina Minta, Gunnar Brinkmalm, Faiez Al Nimer, Eric Thelin, Fredrik Piehl, Mats Tullberg, Anna Jeppsson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Scientific reports - 2020-01-01 -
First amyloid β1-42 certified reference material for re-calibrating commercial
immunoassays
S. Boulo, J. Kuhlmann, Ulf Andreasson, B. Brix, I. Venkataraman, V. Herbst, S. Rutz, E. Manuilova, M. Vandijck, F. Dekeyser, Maria Bjerke, Josef Pannee, J. Charoud-Got, G. Auclair, S. Mazoua, G. Pinski, S. Trapmann, H. Schimmel, H. Emons, M. Quaglia, Erik Portelius, M. Korecka, L. M. Shaw, M. Lame, E. Chambers, H. Vanderstichele, E. Stoops, A. Leinenbach, T. Bittner, R. G. Jenkins, V. Kostanjevecki, P. Lewczuk, Johan Gobom, Henrik Zetterberg, I. Zegers, Kaj Blennow
Alzheimer's and Dementia - 2020-01-01 -
Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle
pathology.
Kaj Blennow, Chun Chen, Claudia Cicognola, Kristin R Wildsmith, Paul T Manser, Sandra M Sanabria Bohorquez, Zhentao Zhang, Boer Xie, Junmin Peng, Oskar Hansson, Hlin Kvartsberg, Erik Portelius, Henrik Zetterberg, Tammaryn Lashley, Gunnar Brinkmalm, Geoffrey A Kerchner, Robby M Weimer, Keqiang Ye, Kina Höglund
Brain : a journal of neurology - 2020-01-01 -
Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid
beta
C. Arber, J. Toombs, C. C. Lovejoy, N. S. Ryan, R. W. Paterson, N. Willumsen, Eleni Gkanatsiou, Erik Portelius, Kaj Blennow, A. Heslegrave, J. M. Schott, J. Hardy, T. Lashley, N. C. Fox, Henrik Zetterberg, S. Wray
Molecular Psychiatry - 2020-01-01 -
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human
brain
I. Alic, P. A. Goh, A. Murray, Erik Portelius, Eleni Gkanatsiou, G. Gough, K. Y. Mok, D. Koschut, R. Brunmeir, Y. J. Yeap, N. L. O'Brien, J. Groet, X. W. Shao, S. Havlicek, N. R. Dunn, Hlin Kvartsberg, Gunnar Brinkmalm, R. Hithersay, C. Startin, S. Hamburg, M. Phillips, K. Pervushin, M. Turmaine, D. Wallon, A. Rovelet-Lecrux, H. Soininen, E. Volpi, J. E. Martin, J. N. Foo, D. L. Becker, A. Rostagno, J. Ghiso, Z. Krsnik, G. Simic, I. Kostovi, D. Mitrecic, P. T. Francis, Kaj Blennow, A. Strydom, J. Hardy, Henrik Zetterberg, D. Nizetic
Molecular Psychiatry - 2020-01-01 -
Perspectives in fluid biomarkers in neurodegeneration from the 2019 biomarkers in neurodegenerative diseases course-a joint PhD student course at University College London and University of
Gothenburg.
Pawel Obrocki, Ayesha Khatun, Deborah Ness, Konstantin Senkevich, Jörg Hanrieder, Federica Capraro, Niklas Mattsson, Ulf Andreasson, Erik Portelius, Nicholas J. Ashton, Kaj Blennow, Michael Schöll, Ross W Paterson, Jonathan M Schott, Henrik Zetterberg
Alzheimer's research & therapy - 2020-01-01 -
Quantification of total apolipoprotein E and its isoforms in cerebrospinal fluid from patients with neurodegenerative
diseases
Karolina Minta, Gunnar Brinkmalm, S. Janelidze, Simon Sjödin, Erik Portelius, E. Stomrud, Henrik Zetterberg, Kaj Blennow, O. Hansson, Ulf Andreasson
Alzheimer's Research & Therapy - 2020-01-01 -
Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species
Aβ5-42.
Tanja Weiffert, Georg Meisl, Patrick Flagmeier, Suman De, Christopher J R Dunning, Birgitta Frohm, Henrik Zetterberg, Kaj Blennow, Erik Portelius, David Klenerman, Christopher M Dobson, Tuomas P J Knowles
ACS chemical neuroscience - 2019-01-01 -
A distinct brain beta amyloid signature in cerebral amyloid angiopathy compared to Alzheimer's
disease.
Eleni Gkanatsiou, Erik Portelius, Christina E Toomey, Kaj Blennow, Henrik Zetterberg, Tammaryn Lashley, Gunnar Brinkmalm
Neuroscience letters - 2019-01-01 -
Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein
fragments.
Marianne K O Grant, Maureen Handoko, Malgorzata Rozga, Gunnar Brinkmalm, Erik Portelius, Kaj Blennow, Karen H Ashe, Kathleen R Zahs, Peng Liu
PloS one - 2019-01-01 -
Fluid-based proteomics targeted on pathophysiological processes and pathologies in neurodegenerative
diseases.
Ann Brinkmalm-Westman, Erik Portelius, Gunnar Brinkmalm, Josef Pannee, Rahil Dahlén, Johan Gobom, Kaj Blennow, Henrik Zetterberg
Journal of neurochemistry - 2019-01-01 -
Cerebrospinal fluid concentrations of extracellular matrix proteins in Alzheimer's
disease
Karolina Minta, Erik Portelius, S. Janelidze, O. Hansson, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Journal of Alzheimer's Disease - 2019-01-01 -
Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain
injury
Karolina Minta, N. C. Cullen, F. A. Nimer, E. P. Thelin, F. Piehl, Marcus Clarin, Mats Tullberg, Anna Jeppsson, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Ulf Andreasson
Clinical Chemistry and Laboratory Medicine - 2019-01-01 -
Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's
brain
Gunnar Brinkmalm, W. Hong, Z. Wang, W. Liu, T. T. O'Malley, X. Sun, M. P. Frosch, D. J. Selkoe, Erik Portelius, Henrik Zetterberg, Kaj Blennow, D. M. Walsh
Brain - 2019-01-01 -
Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement
Disorders.
B Olsson, Erik Portelius, Nicholas C Cullen, Åsa P Sandelius, Henrik Zetterberg, Ulf Andreasson, Kina Höglund, David J Irwin, Murray Grossman, Daniel Weintraub, Alice Chen-Plotkin, David Wolk, Leo McCluskey, Lauren Elman, Leslie M Shaw, Jon B Toledo, Jennifer McBride, Pilar Hernandez-Con, Virginia M-Y Lee, John Q Trojanowski, Kaj Blennow
JAMA neurology - 2019-01-01 -
Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid
pathology.
Åsa P Sandelius, Erik Portelius, Henrik Zetterberg, Uros Rot, Jon B Toledo, Leslie M Shaw, Virginia M Y Lee, David J Irwin, Murray Grossman, Daniel Weintraub, Alice Chen-Plotkin, David A Wolk, Leo McCluskey, Lauren Elman, Vesna Kostanjevecki, Manu Vandijck, Jennifer McBride, John Q Trojanowski, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2019-01-01 -
The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's
disease.
Hlin Kvartsberg, Tammaryn Lashley, Christina E Murray, Gunnar Brinkmalm, Nicholas C Cullen, Kina Höglund, Henrik Zetterberg, Kaj Blennow, Erik Portelius
Acta neuropathologica - 2019-01-01 -
Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and
neuropathology.
Erik Portelius, Bob Olsson, Kina Höglund, Nicholas C Cullen, Hlin Kvartsberg, Ulf Andreasson, Henrik Zetterberg, Åsa P Sandelius, Leslie M Shaw, Virginia M Y Lee, David J Irwin, Murray Grossman, Daniel Weintraub, Alice Chen-Plotkin, David A Wolk, Leo McCluskey, Lauren Elman, Jennifer McBride, Jon B Toledo, John Q Trojanowski, Kaj Blennow
Acta neuropathologica - 2018-01-01 -
Biology/Disease-Driven Initiative on Protein-Aggregation Diseases of the Human Proteome Project: Goals and Progress to
Date
P. J. Boersema, A. Melnik, B. P. C. Hazenberg, M. Rezeli, G. Marko-Varga, J. Kamiie, Erik Portelius, Kaj Blennow, R. A. Zubarev, M. Polymenidou, P. Picotti
Journal of Proteome Research - 2018-01-01 -
Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of A beta
species
F. Oliveira, A. Leuzy, J. Castelhano, K. Chiotis, S. G. Hasselbalch, J. Rinne, A. Mendonca, M. Otto, A. Lleo, I. Santana, J. Johansson, S. Anderl-Straub, C. Arnim, A. Beer, R. Blesa, J. Fortea, H. Sanna-Kaisa, Erik Portelius, Josef Pannee, Henrik Zetterberg, Kaj Blennow, A. P. Moreira, A. Abrunhosa, A. Nordberg, M. Castelo-Branco
Neuroimage-Clinical - 2018-01-01 -
Commutability of the certified reference materials for the standardization of beta-amyloid 1-42 assay in human cerebrospinal fluid: lessons for tau and beta-amyloid 1-40
measurements
Ulf Andreasson, J. Kuhlmann, Josef Pannee, R. M. Umek, E. Stoops, H. Vanderstichele, A. Matzen, M. Vandijck, M. Dauwe, A. Leinenbach, S. Rutz, Erik Portelius, I. Zegers, Henrik Zetterberg, Kaj Blennow
Clinical Chemistry and Laboratory Medicine - 2018-01-01 -
Update on biomarkers for amyloid pathology in Alzheimer's
disease
Nicholas J. Ashton, Michael Schöll, Kerstin Heurling, Eleni Gkanatsiou, Erik Portelius, Kina Höglund, Gunnar Brinkmalm, A Hye, Kaj Blennow, Henrik Zetterberg
Biomarkers in medicine - 2018-01-01 -
Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl
endopeptidase
Bruno Becker, Faisal Hayat Nazir, Gunnar Brinkmalm, Elena Camporesi, Hlin Kvartsberg, Erik Portelius, Martina Boström, Marie Kalm, Kina Höglund, Maria Olsson, Henrik Zetterberg, Kaj Blennow
Molecular Neurodegeneration - 2018-01-01 -
Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of
APP.
Frances K Wiseman, Laura J Pulford, Chris Barkus, Fan Liao, Erik Portelius, Robin Webb, Lucia Chávez-Gutiérrez, Karen Cleverley, Sue Noy, Olivia Sheppard, Toby Collins, Caroline Powell, Claire J Sarell, Matthew Rickman, Xun Choong, Justin L Tosh, Carlos Siganporia, Heather T Whittaker, Floy Stewart, Maria Szaruga, Michael P Murphy, Kaj Blennow, Bart de Strooper, Henrik Zetterberg, David Bannerman, David M Holtzman, Victor L J Tybulewicz, Elizabeth M C Fisher
Brain : a journal of neurology - 2018-01-01 -
The presubiculum is preserved from neurodegenerative changes in Alzheimer's
disease
C. E. Murray, P. Gami-Patel, Eleni Gkanatsiou, Gunnar Brinkmalm, Erik Portelius, O. Wirths, W. Heywood, Kaj Blennow, J. Ghiso, J. L. Holton, K. Mills, Henrik Zetterberg, T. Revesz, T. Lashley
Acta Neuropathologica Communications - 2018-01-01 -
Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole
Insecticides.
Morgane Cam, Emilie Durieu, Marion Bodin, Antigoni Manousopoulou, Svenja Koslowski, Natalia Vasylieva, Bogdan Barnych, Bruce D Hammock, Bettina Bohl, Philipp Koch, Chiori Omori, Kazuo Yamamoto, Saori Hata, Toshiharu Suzuki, Frank Karg, Patrick Gizzi, Vesna Erakovic Haber, Vlatka Bencetic Mihaljevic, Branka Tavcar, Erik Portelius, Josef Pannee, Kaj Blennow, Henrik Zetterberg, Spiros D Garbis, Pierrick Auvray, Hermeto Gerber, Jeremy Fraering, Patrick C Fraering, Laurent Meijer
Journal of Alzheimer's disease : JAD - 2018-01-01 -
CSF neurofilament light concentration is increased in presymptomatic CHMP2B mutation
carriers
Nina Rostgaard, Peter Roos, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Anja H Simonsen, Jørgen E Nielsen
Neurology - 2018-01-01 -
CSF neurogranin or tau distinguish typical and atypical Alzheimer
disease
H. Wellington, R. W. Paterson, A. Suarez-Gonzalez, T. Poole, C. Frost, U. Sjobom, C. F. Slattery, N. K. Magdalinou, M. Lehmann, Erik Portelius, N. C. Fox, Kaj Blennow, Henrik Zetterberg, J. M. Schott
Annals of Clinical and Translational Neurology - 2018-01-01 -
Expanding the cerebrospinal fluid
endopeptidome
Karl Hansson, Tobias Skillbäck, Elin Pernevik, Silke Kern, Erik Portelius, Kina Höglund, Gunnar Brinkmalm, Jessica Holmén Larsson, Kaj Blennow, Henrik Zetterberg, Johan Gobom
Proteomics - 2017-01-01 -
Proteomic studies of cerebrospinal fluid biomarkers of Alzheimer's disease: an
update.
Erik Portelius, Gunnar Brinkmalm, Josef Pannee, Henrik Zetterberg, Kaj Blennow, Rahil Dahlén, Ann Brinkmalm-Westman, Johan Gobom
Expert review of proteomics - 2017-01-01 -
Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric
Aβ.
Lotta Agholme, Marcus Clarin, Eleni Gkanatsiou, Petronella Kettunen, Jasmine Chebli, Gunnar Brinkmalm, Kaj Blennow, Petra Bergström, Erik Portelius, Henrik Zetterberg
Molecular and cellular neurosciences - 2017-01-01 -
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's
disease.
Jay Rasmussen, Jasmin Mahler, Natalie Beschorner, Stephan A Kaeser, Lisa M Häsler, Frank Baumann, Sofie Nyström, Erik Portelius, Kaj Blennow, Nick C Fox, Diego Sepulveda-Falla, Markus Glatzel, Adrian L Oblak, Bernardino Ghetti, K Peter R Nilsson, Per Hammarström, Matthias Staufenbiel, Lary C Walker, Mathias Jucker
Proceedings of the National Academy of Sciences of the United States of America - 2017-01-01 -
Effect of physical exercise on markers of neuronal dysfunction in cerebrospinal fluid in patients with Alzheimer's
disease
C. S. Jensen, Erik Portelius, P. Høgh, L. Wermuth, Kaj Blennow, Henrik Zetterberg, S. G. Hasselbalch, A. H. Simonsen
Alzheimer's and Dementia: Translational Research and Clinical Interventions - 2017-01-01 -
Alzheimer's disease markers in the aged sheep (Ovis
aries).
Suzanne J Reid, Natasha E Mckean, Kristen Henty, Erik Portelius, Kaj Blennow, Skye R Rudiger, C Simon Bawden, Renee R Handley, Paul J Verma, Richard L M Faull, Henry J Waldvogel, Henrik Zetterberg, Russell G Snell
Neurobiology of aging - 2017-01-01 -
Tau oligomers in cerebrospinal fluid in Alzheimer's
disease.
Urmi Sengupta, Erik Portelius, Oskar Hansson, Kathleen Farmer, Diana Castillo-Carranza, Randall Woltjer, Henrik Zetterberg, Douglas Galasko, Kaj Blennow, Rakez Kayed
Annals of clinical and translational neurology - 2017-01-01 -
Astroglial activation and altered amyloid metabolism in human repetitive
concussion.
Pashtun Shahim, Yelverton Tegner, Niklas Marklund, Kina Höglund, Erik Portelius, David L Brody, Kaj Blennow, Henrik Zetterberg
Neurology - 2017-01-01 -
Absolute Quantification of Aβ1-42 in CSF Using a Mass Spectrometric Reference Measurement
Procedure.
Josef Pannee, Kaj Blennow, Henrik Zetterberg, Erik Portelius
Journal of visualized experiments : JoVE - 2017-01-01 -
CSF Aβ1-42 - an excellent but complicated Alzheimer's biomarker - a route to
standardisation.
Julia Kuhlmann, Ulf Andreasson, Josef Pannee, Maria Bjerke, Erik Portelius, Andreas Leinenbach, Tobias Bittner, Magdalena Korecka, Rand G Jenkins, Hugo Vanderstichele, Erik Stoops, Piotr Lewczuk, Leslie M Shaw, Ingrid Zegers, Heinz Schimmel, Henrik Zetterberg, Kaj Blennow
Clinica chimica acta; international journal of clinical chemistry - 2017-01-01 -
Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's
Disease.
Philip W Brownjohn, James Smith, Erik Portelius, Lutgarde Serneels, Hlin Kvartsberg, Bart De Strooper, Kaj Blennow, Henrik Zetterberg, Frederick J Livesey
Stem cell reports - 2017-01-01 -
Ex vivo (18)O-labeling mass spectrometry identifies a peripheral amyloid β clearance
pathway.
Erik Portelius, Niklas Mattson, Josef Pannee, Henrik Zetterberg, Magnus Gisslén, Hugo Vanderstichele, Eleni Gkanatsiou, Gabriela A N Crespi, Michael W Parker, Luke A Miles, Johan Gobom, Kaj Blennow
Molecular neurodegeneration - 2017-01-01 -
Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic
study.
Antoine Leuzy, Konstantinos Chiotis, Steen G Hasselbalch, Juha O Rinne, Alexandre de Mendonça, Markus Otto, Alberto Lleó, Miguel Castelo-Branco, Isabel Santana, Jarkko Johansson, Sarah Anderl-Straub, Christine A F von Arnim, Ambros Beer, Rafael Blesa, Juan Fortea, Sanna-Kaisa Herukka, Erik Portelius, Josef Pannee, Henrik Zetterberg, Kaj Blennow, Agneta Nordberg
Brain : a journal of neurology - 2016-01-01 -
Amyloid precursor protein expression and processing are differentially regulated during cortical neuron
differentiation
Petra Bergström, Lotta Agholme, Faisal Hayat Nazir, Tugce Munise Satir, J. Toombs, H. Wellington, Joakim Strandberg, Thomas Olsson Bontell, Hlin Kvartsberg, Maria Holmström, Cecilia Boreström, Stina Simonsson, T. Kunath, Anders Lindahl, Kaj Blennow, Eric Hanse, Erik Portelius, S. Wray, Henrik Zetterberg
Scientific Reports - 2016-01-01 -
Cerebrospinal fluid-induced retardation of amyloid beta aggregation correlates with Alzheimer's disease and the APOE epsilon 4
allele
Eden R. Padayachee, Henrik Zetterberg, Erik Portelius, Jan Borén, J. L. Molinuevo, N. Andreasen, R. Cukalevski, S. Linse, Kaj Blennow, Ulf Andreasson
Brain Research - 2016-01-01 -
Neurochemical Aftermath of Repetitive Mild Traumatic Brain
Injury.
Pashtun Shahim, Yelverton Tegner, Bengt Gustafsson, Magnus Gren, Johan Ärlig, Martin Olsson, Niklas Lehto, Åsa Engström, Kina Höglund, Erik Portelius, Henrik Zetterberg, Kaj Blennow
JAMA neurology - 2016-01-01 -
Reference measurement procedure for CSF Aβ1-42 and the CSF Aβ1-42 /Aβ1-40 ratio - a cross-validation study against Amyloid
PET.
Josef Pannee, Erik Portelius, Lennart Minthon, Johan Gobom, Ulf Andreasson, Henrik Zetterberg, Oskar Hansson, Kaj Blennow
Journal of neurochemistry - 2016-01-01 -
Cerebrospinal Fluid Amyloid Beta and Tau Concentrations Are Not Modulated by 16 Weeks of Moderate- to High-Intensity Physical Exercise in Patients with Alzheimer
Disease.
Camilla Steen Jensen, Erik Portelius, Volkert Siersma, Peter Høgh, Lene Wermuth, Kaj Blennow, Henrik Zetterberg, Gunhild Waldemar, Steen Gregers Hasselbalch, Anja Hviid Simonsen
Dementia and geriatric cognitive disorders - 2016-01-01 -
Specific Triazine Herbicides Induce Amyloid-β42
Production.
Erik Portelius, Emilie Durieu, Marion Bodin, Morgane Cam, Josef Pannee, Charlotte Leuxe, Aloϊse Mabondzo, Nassima Oumata, Hervé Galons, Jung Yeol Lee, Young-Tae Chang, Kathrin Stϋber, Philipp Koch, Gaëlle Fontaine, Marie-Claude Potier, Antigoni Manousopoulou, Spiros Garbis, Adrian Covaci, Debby Van Dam, Peter De Deyn, Frank Karg, Marc Flajolet, Chiori Omori, Saori Hata, Toshiharu Suzuki, Kaj Blennow, Henrik Zetterberg, Laurent Meijer
Journal of Alzheimer's disease : JAD - 2016-01-01 -
Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's
disease.
Niklas Mattsson, Philip S Insel, Sebastian Palmqvist, Erik Portelius, Henrik Zetterberg, Michael Weiner, Kaj Blennow, Oskar Hansson
EMBO molecular medicine - 2016-01-01 -
Assessing the commutability of reference material formats for the harmonization of amyloid beta
measurements.
Maria Bjerke, Ulf Andreasson, Julia Kuhlmann, Erik Portelius, Josef Pannee, Piotr Lewczuk, Robert M Umek, Eugeen Vanmechelen, Hugo Vanderstichele, Erik Stoops, Jennifer Lewis, Manu Vandijck, Vesna Kostanjevecki, Andreas Jeromin, Salvatore J Salamone, Oliver Schmidt, Anja Matzen, Kairat Madin, Udo Eichenlaub, Tobias Bittner, Leslie M Shaw, Ingrid Zegers, Henrik Zetterberg, Kaj Blennow
Clinical chemistry and laboratory medicine : CCLM / FESCC - 2016-01-01 -
CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and
meta-analysis.
Bob Olsson, Ronald Lautner, Ulf Andreasson, Annika Öhrfelt, Erik Portelius, Maria Bjerke, Mikko Hölttä, Christoffer Rosén, Caroline Olsson, Gabrielle Strobel, Elizabeth Wu, Kelly Dakin, Max Petzold, Kaj Blennow, Henrik Zetterberg
The Lancet. Neurology - 2016-01-01 -
Increased CSF neurogranin concentration is specific to Alzheimer
disease.
Henrietta Wellington, Ross W Paterson, Erik Portelius, Ulrika Törnqvist, Nadia Magdalinou, Nick C Fox, Kaj Blennow, Jonathan M Schott, Henrik Zetterberg
Neurology - 2016-01-01 -
A single dose of the gamma-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in
humans
Mikko Hölttä, R. A. Dean, E. Siemers, K. G. Mawuenyega, W. Sigurdson, P. C. May, D. M. Holtzman, Erik Portelius, Henrik Zetterberg, R. J. Bateman, Kaj Blennow, Johan Gobom
Alzheimers Research & Therapy - 2016-01-01 -
Round robin test on quantification of amyloid-β 1-42 in cerebrospinal fluid by mass
spectrometry.
Josef Pannee, Johan Gobom, Leslie M Shaw, Magdalena Korecka, Erin E Chambers, Mary Lame, Rand Jenkins, William Mylott, Maria C Carrillo, Ingrid Zegers, Henrik Zetterberg, Kaj Blennow, Erik Portelius
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2016-01-01 -
Association of Cerebrospinal Fluid Neurofilament Light Concentration With Alzheimer Disease
Progression.
Henrik Zetterberg, Tobias Skillbäck, Niklas Mattsson, John Q Trojanowski, Erik Portelius, Leslie M Shaw, Michael W Weiner, Kaj Blennow
JAMA neurology - 2016-01-01 -
APLP1 as a cerebrospinal fluid biomarker for gamma-secretase modulator
treatment
Simon Sjödin, M. Mercken, Henrik Zetterberg, H. Borghys, Kaj Blennow, Erik Portelius
Alzheimers Research & Therapy - 2015-01-01 -
Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's
disease.
Hlin Kvartsberg, Flora H Duits, Martin Ingelsson, Niels Andreasen, Annika Öhrfelt, Gunnar Brinkmalm, Lars Lannfelt, Lennart Minthon, Oskar Hansson, Ulf Andreasson, Charlotte E Teunissen, Philip Scheltens, Wiesje M van der Flier, Henrik Zetterberg, Erik Portelius, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2015-01-01 -
C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's
disease.
Ann De Vos, Dirk Jacobs, Hanne Struyfs, Erik Fransen, Erik Portelius, Ulf Andreasson, Didier De Surgeloose, Daniëlle Hernalsteen, Kristel Sleegers, Caroline Robberecht, Christine Van Broeckhoven, Henrik Zetterberg, Kaj Blennow, Sebastiaan Engelborghs, Eugeen Vanmechelen
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2015-01-01 -
Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's
disease
K. Hellwig, Hlin Kvartsberg, Erik Portelius, Ulf Andreasson, T. J. Oberstein, P. Lewczuk, Kaj Blennow, J. Kornhuber, J. M. Maler, Henrik Zetterberg, P. Spitzer
Alzheimers Research & Therapy - 2015-01-01 -
Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer's
disease.
Erik Portelius, Henrik Zetterberg, Tobias Skillbäck, Ulrika Törnqvist, Ulf Andreasson, John Q Trojanowski, Michael W Weiner, Leslie M Shaw, Niklas Mattsson, Kaj Blennow
Brain : a journal of neurology - 2015-01-01 -
The aqueous phase of Alzheimer's disease brain contains assemblies built from similar to 4 and similar to 7 kDa A beta
species
J. M. Mc Donald, T. T. O'Malley, W. Liu, A. J. Mably, Gunnar Brinkmalm, Erik Portelius, W. M. Wittbold, M. P. Frosch, D. M. Walsh
Alzheimers & Dementia - 2015-01-01 -
Case Report of Complex Amyotrophic Lateral Sclerosis with Cognitive Impairment and Cortical Amyloid
Deposition.
Karim Farid, Stephen F Carter, Elena Rodriguez-Vieitez, Ove Almkvist, Pia Andersen, Anders Wall, Kaj Blennow, Erik Portelius, Henrik Zetterberg, Agneta Nordberg
Journal of Alzheimer's disease : JAD - 2015-01-01 -
Alzheimer's disease - Recent biomarker developments in relation to updated diagnostic
criteria.
Kina Höglund, Anthony Fourier, Armand Perret-Liaudet, Henrik Zetterberg, Kaj Blennow, Erik Portelius
Clinica chimica acta; international journal of clinical chemistry - 2015-01-01 -
First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene
expression.
Damian M Cummings, Wenfei Liu, Erik Portelius, Sevinç Bayram, Marina Yasvoina, Sui-Hin Ho, Hélène Smits, Shabinah S Ali, Rivka Steinberg, Chrysia-Maria Pegasiou, Owain T James, Mar Matarin, Jill C Richardson, Henrik Zetterberg, Kaj Blennow, John A Hardy, Dervis A Salih, Frances A Edwards
Brain : a journal of neurology - 2015-01-01 -
Pre-analytical and analytical factors influencing Alzheimer's disease cerebrospinal fluid biomarker
variability.
Anthony Fourier, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Isabelle Quadrio, Armand Perret-Liaudet
Clinica chimica acta; international journal of clinical chemistry - 2015-01-01 -
Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy
controls
Hlin Kvartsberg, Erik Portelius, Ulf Andreasson, Gunnar Brinkmalm, K. Hellwig, N. Lelental, J. Kornhuber, O. Hansson, L. Minthon, P. Spitzer, J. M. Maler, Henrik Zetterberg, Kaj Blennow, P. Lewczuk
Alzheimers Research & Therapy - 2015-01-01 -
APP Metabolism Regulates Tau Proteostasis in Human Cerebral Cortex
Neurons
S. Moore, L. D. B. Evans, T. Andersson, Erik Portelius, J. Smith, T. B. Dias, N. Saurat, A. McGlade, P. Kirwan, Kaj Blennow, J. Hardy, Henrik Zetterberg, F. J. Livesey
Cell Reports - 2015-01-01 -
Explorative and targeted neuroproteomics in Alzheimer's
disease.
Ann Brinkmalm-Westman, Erik Portelius, Annika Öhrfelt, Gunnar Brinkmalm, Ulf Andreasson, Johan Gobom, Kaj Blennow, Henrik Zetterberg
Biochimica et biophysica acta - 2015-01-01 -
Brain Amyloid-Beta Fragment Signatures in Pathological Ageing and Alzheimer's Disease by Hybrid Immunoprecipitation Mass
Spectrometry
Erik Portelius, T. Lashley, Anna Westerlund, Rita Persson, N. C. Fox, Kaj Blennow, T. Revesz, Henrik Zetterberg
Neurodegenerative Diseases - 2015-01-01 -
β-site amyloid precursor protein-cleaving enzyme 1(BACE1) inhibitor treatment induces Aβ5-X peptides through alternative amyloid precursor protein
cleavage.
Erik Portelius, Robert A Dean, Ulf Andreasson, Niklas Mattsson, Annie Westerlund, Maria Olsson, Ronald Bradley Demattos, Margaret M Racke, Henrik Zetterberg, Patrick C May, Kaj Blennow
Alzheimer's research & therapy - 2014-01-01 -
Characterization of the Effect of a Novel gamma-secretase Modulator on A beta: A Clinically Translatable
Model
Erik Portelius, P. Appelkvist, K. Stromberg, Kina Höglund
Current pharmaceutical design - 2014-01-01 -
Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for Apolipoprotein e
isoforms
E. Martínez-Morillo, H. M. Nielsen, I. Batruch, A. P. Drabovich, I. Begcevic, M. F. Lopez, L. Minthon, G. Bu, Niklas Mattsson, Erik Portelius, O. Hansson, E. P. Diamandis
Journal of Proteome Research - 2014-01-01 -
Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal
fluid.
Sarah K Fritschi, Franziska Langer, Stephan A Kaeser, Luis F Maia, Erik Portelius, Dorothea Pinotsi, Clemens F Kaminski, David T Winkler, Walter Maetzler, Kathy Keyvani, Philipp Spitzer, Jens Wiltfang, Gabriele S Kaminski Schierle, Henrik Zetterberg, Matthias Staufenbiel, Mathias Jucker
Brain : a journal of neurology - 2014-01-01 -
Exploring Alzheimer molecular pathology in Down's syndrome cerebrospinal
fluid.
Erik Portelius, Hilkka Soininen, Ulf Andreasson, Henrik Zetterberg, Rita Persson, Gösta Karlsson, Kaj Blennow, Sanna-Kaisa Herukka, Niklas Mattsson
Neuro-degenerative diseases - 2014-01-01 -
Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-β in cerebrospinal
fluid.
Andreas Leinenbach, Josef Pannee, Thomas Dülffer, Andreas Huber, Tobias Bittner, Ulf Andreasson, Johan Gobom, Henrik Zetterberg, Uwe Kobold, Erik Portelius, Kaj Blennow
Clinical chemistry - 2014-01-01 -
The amyloid-β degradation pattern in plasma-A possible tool for clinical trials in Alzheimer's
disease
Josef Pannee, Ulrika Törnqvist, Annie Westerlund, M. Ingelsson, L. Lannfelt, Gunnar Brinkmalm, Rita Persson, Johan Gobom, Johan Svensson, Per Johansson, Henrik Zetterberg, Kaj Blennow, Erik Portelius
Neuroscience Letters - 2014-01-01 -
Altered Cerebrospinal Fluid Levels of Amyloid beta and Amyloid Precursor-Like Protein 1 Peptides in Down's
Syndrome
Erik Portelius, Mikko Hölttä, H. Soininen, Maria Bjerke, Henrik Zetterberg, Anni Westerlund, S. K. Herukka, Kaj Blennow, Niklas Mattsson
Neuromolecular medicine - 2014-01-01 -
Mass spectrometric characterization of amyloid-β species in the 7PA2 cell model of Alzheimer's
disease.
Erik Portelius, Maria Olsson, Gunnar Brinkmalm, Ulla Rüetschi, Niklas Mattsson, Ulf Andreasson, Johan Gobom, Ann Brinkmalm-Westman, Mikko Hölttä, Kaj Blennow, Henrik Zetterberg
Journal of Alzheimer's disease : JAD - 2013-01-01 -
Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's
disease.
Jere E Meredith, Sethu Sankaranarayanan, Valerie Guss, Anthony J Lanzetti, Flora Berisha, Robert J Neely, J Randall Slemmon, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Holly Soares, Michael Ahlijanian, Charles F Albright
PloS one - 2013-01-01 -
Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple
sclerosis.
Kristin Augutis, Markus Axelsson, Erik Portelius, Gunnar Brinkmalm, Ulf Andreasson, Mikael K Gustavsson, Clas Malmeström, Jan Lycke, Kaj Blennow, Henrik Zetterberg, Niklas Mattsson
Multiple sclerosis (Houndmills, Basingstoke, England) - 2013-01-01 -
A selected reaction monitoring (SRM)-based method for absolute quantification of Aβ38, Aβ40, and Aβ42 in cerebrospinal fluid of Alzheimer's Disease patients and healthy
controls.
Josef Pannee, Erik Portelius, Madalina Oppermann, Alan Atkins, Martin Hornshaw, Ingrid Zegers, Peter Höjrup, Lennart Minthon, Oskar Hansson, Henrik Zetterberg, Kaj Blennow, Johan Gobom
Journal of Alzheimer's Disease - 2013-01-01 -
Aβ1-15/16 as a potential diagnostic marker in neurodegenerative
diseases.
Magdalena Nutu, Philippe Bourgeois, Henrik Zetterberg, Erik Portelius, Ulf Andreasson, Stéphane Parent, Francesco Lipari, Sara Hall, Radu Constantinescu, Oskar Hansson, Kaj Blennow
Neuromolecular medicine - 2013-01-01 -
Analysis of Amino-Terminal Variants of Amyloid-β Peptides by Capillary Isoelectric Focusing
Immunoassay.
Ute Haußmann, Olaf Jahn, Philipp Linning, Christin Janßen, Thomas Liepold, Erik Portelius, Henrik Zetterberg, Chris Bauer, Johannes Schuchhardt, Hans-Joachim Knölker, Hans Klafki, Jens Wiltfang
Analytical chemistry - 2013-01-01 -
Soluble amyloid precursor protein α and β in CSF in Alzheimer's
disease.
Gunnar Brinkmalm, Ann Brinkmalm-Westman, Philippe Bourgeois, Rita Persson, Oskar Hansson, Erik Portelius, Marc Mercken, Ulf Andreasson, Stéphane Parent, Francesco Lipari, Annika Öhrfelt, Maria Bjerke, Lennart Minthon, Henrik Zetterberg, Kaj Blennow, Magdalena Nutu
Brain research - 2013-01-01 -
A Patient with Posterior Cortical Atrophy Possesses a Novel Mutation in the Presenilin 1
Gene
E. J. Sitek, E. Narozanska, B. Peplonska, S. Filipek, A. Barczak, M. Styczynska, K. Mlynarczyk, B. Brockhuis, Erik Portelius, D. Religa, M. Barcikowska, J. Slawek, C. Zekanowski
Plos One - 2013-01-01 -
Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and
serum
B. Krastins, A. Prakash, D. A. Sarracino, D. Nedelkov, E. E. Niederkofler, U. A. Kiernan, R. Nelson, M. S. Vogelsang, G. Vadali, A. Garces, J. N. Sutton, S. Peterman, G. Byram, B. Darbouret, J. R. Perusse, N. G. Seidah, B. Coulombe, Johan Gobom, Erik Portelius, Josef Pannee, Kaj Blennow, V. Kulasingam, L. Couchman, C. Moniz, M. F. Lopez
Clinical Biochemistry - 2013-01-01 -
The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's
disease
Erik Portelius, Juan Fortea, Jose Luis Molinuevo, Mikael K Gustavsson, Ulf Andreasson, Raquel Sanchez-Valle
Molecular Medicine Reports - 2012-01-01 -
Amyloid-β metabolism in Niemann-Pick C disease models and
patients.
Niklas Mattsson, Maria Olsson, Mikael K Gustavsson, Marko Kosicek, Martina Malnar, Jan-Eric Månsson, Maria K. Blomqvist, Johan Gobom, Ulf Andreasson, Gunnar Brinkmalm, Charles Vite, Silva Hecimovic, Caroline Hastings, Kaj Blennow, Henrik Zetterberg, Erik Portelius
Metabolic brain disease - 2012-01-01 -
BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous
system.
Niklas Mattsson, Lawrence Rajendran, Henrik Zetterberg, Mikael K Gustavsson, Ulf Andreasson, Maria Olsson, Gunnar Brinkmalm, Johan Lundkvist, Laura H Jacobson, Ludovic Perrot, Ulf Neumann, Herman Borghys, Marc Mercken, Deborah Dhuyvetter, Fredrik Jeppsson, Kaj Blennow, Erik Portelius
PloS one - 2012-01-01 -
Longitudinal cerebrospinal fluid biomarkers over four years in mild cognitive
impairment.
Niklas Mattsson, Erik Portelius, Sindre Rolstad, Mikael K Gustavsson, Ulf Andreasson, Mats Stridsberg, Anders Wallin, Kaj Blennow, Henrik Zetterberg
Journal of Alzheimer's disease : JAD - 2012-01-01 -
Evaluation of the performance of novel Aβ isoforms as theragnostic markers in Alzheimer's disease: from the cell to the
patient.
Erik Portelius, Mikael K Gustavsson, Henrik Zetterberg, Ulf Andreasson, Kaj Blennow
Neuro-degenerative diseases - 2012-01-01 -
Multiplexing and multivariate analysis in
neurodegeneration.
Ulf Andreasson, Erik Portelius, Josef Pannee, Henrik Zetterberg, Kaj Blennow
Methods (San Diego, Calif.) - 2012-01-01 -
Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's
disease.
Erik Portelius, Henrik Zetterberg, Robert A Dean, Alexandre Marcil, Philippe Bourgeois, Magdalena Nutu, Ulf Andreasson, Eric Siemers, Kwasi G Mawuenyega, Wendy C Sigurdson, Patrick C May, Steven M Paul, David M Holtzman, Kaj Blennow, Randall J Bateman
Journal of Alzheimer's disease : JAD - 2012-01-01 -
Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ
production.
Johanna Wanngren, Jan Ottervald, Santiago Parpal, Erik Portelius, Kia Strömberg, Tomas Borgegård, Rebecka Klintenberg, Anders Juréus, Jenny Blomqvist, Kaj Blennow, Henrik Zetterberg, Johan Lundkvist, Susanne Rosqvist, Helena Karlström
The Journal of biological chemistry - 2012-01-01 -
Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer
disease.
Vladimir Coric, Christopher H van Dyck, Stephen Salloway, Niels Andreasen, Mark Brody, Ralph W Richter, Hilkka Soininen, Stephen Thein, Thomas Shiovitz, Gary Pilcher, Susan Colby, Linda Rollin, Randy Dockens, Chahin Pachai, Erik Portelius, Ulf Andreasson, Kaj Blennow, Holly Soares, Charles Albright, Howard H Feldman, Robert M Berman
Archives of neurology - 2012-01-01 -
Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid
β42.
Niklas Mattsson, Ingrid Zegers, Ulf Andreasson, Maria Bjerke, Marinus A Blankenstein, Robert Bowser, Maria C Carrillo, Johan Gobom, Theresa Heath, Rand Jenkins, Andreas Jeromin, June Kaplow, Daniel Kidd, Omar F Laterza, Andrew Lockhart, Michael P Lunn, Robert L Martone, Kevin Mills, Josef Pannee, Marianne Ratcliffe, Leslie M Shaw, Adam J Simon, Holly Soares, Charlotte E Teunissen, Marcel M Verbeek, Robert M Umek, Hugo Vanderstichele, Henrik Zetterberg, Kaj Blennow, Erik Portelius
Biomarkers in medicine - 2012-01-01 -
Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer
disease.
Jessica L Wittnam, Erik Portelius, Henrik Zetterberg, Mikael K Gustavsson, Stephan Schilling, Birgit Koch, Hans-Ulrich Demuth, Kaj Blennow, Oliver Wirths, Thomas A Bayer
The Journal of biological chemistry - 2012-01-01 -
An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal
fluid.
Gunnar Brinkmalm, Erik Portelius, Annika Öhrfelt, Niklas Mattsson, Rita Persson, Mikael K Gustavsson, Charles H Vite, Johan Gobom, Jan-Eric Månsson, Jonas Nilsson, Adnan Halim, Göran Larson, Ulla Rüetschi, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm-Westman
Journal of mass spectrometry : JMS - 2012-01-01 -
Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576
mice.
Kathryn Rogers, Kevin M Felsenstein, Lori Hrdlicka, Zhiming Tu, Faris Albayya, Winnie Lee, Sarah Hopp, Mary-Jo Miller, Darcie Spaulding, Zhiyong Yang, Hilliary Hodgdon, Scott Nolan, Melody Wen, Don Costa, Jean-Francois Blain, Emily Freeman, Bart De Strooper, Veerle Vulsteke, Louise Scrocchi, Henrik Zetterberg, Erik Portelius, Birgit Hutter-Paier, Daniel Havas, Michael Ahlijanian, Dorothy Flood, Liza Leventhal, Gideon Shapiro, Holger Patzke, Richard Chesworth, Gerhard Koenig
Molecular neurodegeneration - 2012-01-01 -
A novel pathway for amyloid precursor protein
processing.
Erik Portelius, Erik Price, Gunnar Brinkmalm, Mark Stiteler, Maria Olsson, Rita Persson, Henrik Zetterberg, Ann Brinkmalm-Westman, Adam J Simon, Kaj Blennow
Neurobiology of aging - 2011-01-01 -
Found in translation: a blood-based test for Niemann-Pick type
C1.
Niklas Mattsson, Bob Olsson, Ulf Andreasson, Erik Portelius, Henrik Zetterberg
Biomarkers in medicine - 2011-01-01 -
A new member in the biomarker discovery
toolbox.
Niklas Mattsson, Bob Olsson, Ulf Andreasson, Erik Portelius, Henrik Zetterberg
Biomarkers in medicine - 2011-01-01 -
Troponin T: more than acute myocardial
infarction.
Niklas Mattsson, Bob Olsson, Ulf Andreasson, Erik Portelius, Henrik Zetterberg
Biomarkers in medicine - 2011-01-01 -
Growth factors in Parkinson's
disease.
Niklas Mattsson, Bob Olsson, Ulf Andreasson, Erik Portelius, Henrik Zetterberg
Biomarkers in medicine - 2011-01-01 -
It is all about
clearance.
Niklas Mattsson, Bob Olsson, Ulf Andreasson, Erik Portelius, Henrik Zetterberg
Biomarkers in medicine - 2011-01-01 -
Novel Aβ Isoforms in Alzheimer´s Disease - Their Role in Diagnosis and
Treatment.
Erik Portelius, Niklas Mattsson, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg
Current pharmaceutical design - 2011-01-01 -
Characterization of the brain β-amyloid isoform pattern at different ages of Tg2576
mice.
Tamanna Mustafiz, Erik Portelius, Mikael K Gustavsson, Mikko Hölttä, Henrik Zetterberg, Kaj Blennow, Agneta Nordberg, Christina Unger Lithner
Neuro-degenerative diseases - 2011-01-01 -
Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid {beta}-peptides in human cerebrospinal
fluid.
Adnan Halim, Gunnar Brinkmalm, Ulla Rüetschi, Ann Brinkmalm-Westman, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Göran Larson, Jonas Nilsson
Proceedings of the National Academy of Sciences of the United States of America - 2011-01-01 -
Acute effect on the Aβ isoform pattern in CSF in response to γ-secretase modulator and inhibitor treatment in
dogs.
Erik Portelius, Bianca Van Broeck, Ulf Andreasson, Mikael K Gustavsson, Marc Mercken, Henrik Zetterberg, Herman Borghys, Kaj Blennow
Journal of Alzheimer's disease : JAD - 2010-01-01 -
Identification of novel N-terminal fragments of amyloid precursor protein in cerebrospinal
fluid.
Erik Portelius, Gunnar Brinkmalm, Ai Jun Tran, Ulf Andreasson, Henrik Zetterberg, Ann Brinkmalm-Westman, Kaj Blennow, Annika Öhrfelt Olsson
Experimental neurology - 2010-01-01 -
Confounding factors influencing amyloid Beta concentration in cerebrospinal
fluid.
Maria Bjerke, Erik Portelius, Lennart Minthon, Anders Wallin, Henrik Anckarsäter, Rolf Anckarsäter, Niels Andreasen, Henrik Zetterberg, Ulf Andreasson, Kaj Blennow
International journal of Alzheimer's disease - 2010-01-01 -
Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's
disease.
Erik Portelius, Nenad Bogdanovic, Mikael K Gustavsson, Inga Volkmann, Gunnar Brinkmalm, Henrik Zetterberg, Bengt Winblad, Kaj Blennow
Acta neuropathologica - 2010-01-01 -
A novel Aβ isoform pattern in CSF reflects γ-secretase inhibition in Alzheimer
disease
Erik Portelius, Robert A Dean, Mikael K Gustavsson, Ulf Andreasson, Henrik Zetterberg, Eric Siemers, Kaj Blennow
Alzheimer's research & therapy - 2010-01-01 -
Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's
disease.
Erik Portelius, Ulf Andreasson, John M Ringman, Katharina Buerger, Jonny Daborg, Peder Buchhave, Oskar Hansson, Andreas Harmsen, Mikael K Gustavsson, Eric Hanse, Douglas Galasko, Harald Hampel, Kaj Blennow, Henrik Zetterberg
Molecular neurodegeneration - 2010-01-01 -
Development of a targeted Aβ proteomic platform for Alzheimer´s disease – an exploration for diagnostic and theragnostic markers using the Thermo Scientific KingFisher mL and mass
spectrometry
Erik Portelius, Kaj Blennow
Thermo Scientific Technical Note. AN-PS-KFMLAD_1110. - 2010-01-01 -
Effects of gamma-Secretase Inhibition on the Amyloid beta Isoform Pattern in a Mouse Model of Alzheimer's
Disease.
Erik Portelius, Bin Zhang, Mikael K Gustavsson, Gunnar Brinkmalm, Ann Brinkmalm-Westman, Henrik Zetterberg, Virginia M-Y Lee, John Q Trojanowski, Kaj Blennow
Neuro-degenerative diseases - 2009-01-01 -
Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative
diseases.
Ann Brinkmalm-Westman, Ulla Rüetschi, Erik Portelius, Ulf Andreasson, Gunnar Brinkmalm, Gösta Karlsson, Sarah Hansson, Henrik Zetterberg, Kaj Blennow
Frontiers in bioscience : a journal and virtual library - 2009-01-01 -
Synaptic retrogenesis and amyloid-beta in Alzheimer's
disease.
Pontus Wasling, Jonny Daborg, Ilse Riebe, My Andersson, Erik Portelius, Kaj Blennow, Eric Hanse, Henrik Zetterberg
Journal of Alzheimer's disease : JAD - 2009-01-01 -
A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic
mice.
Ola Philipson, Per Hammarström, K Peter R Nilsson, Erik Portelius, Tommie Olofsson, Martin Ingelsson, Bradley T Hyman, Kaj Blennow, Lars Lannfelt, Hannu Kalimo, Lars N G Nilsson
Neurobiology of aging - 2009-01-01 -
Targeted Abeta proteomics - A tool to study the pathogenesis of Alzheimer’s
disease
Erik Portelius
- 2009-01-01 -
Identification of novel APP/Abeta isoforms in human cerebrospinal
fluid.
Erik Portelius, Gunnar Brinkmalm, Ai Jun Tran, Henrik Zetterberg, Ann Brinkmalm-Westman, Kaj Blennow
Neuro-degenerative diseases - 2009-01-01 -
Targeted proteomics in Alzheimer's disease: focus on
amyloid-beta.
Erik Portelius, Henrik Zetterberg, Johan Gobom, Ulf Andreasson, Kaj Blennow
Expert review of proteomics - 2008-01-01 -
Characterization of tau in cerebrospinal fluid using mass
spectrometry.
Erik Portelius, Sara Folkesson Hansson, Ai Jun Tran, Henrik Zetterberg, Pierre Grognet, Eugeen Vanmechelen, Kina Höglund, Gunnar Brinkmalm, Ann Brinkmalm-Westman, Eckhard Nordhoff, Kaj Blennow, Johan Gobom
Journal of proteome research - 2008-01-01 -
Clinical proteomics in neurodegenerative
disorders.
Henrik Zetterberg, Ulla Rüetschi, Erik Portelius, Gunnar Brinkmalm, Ulf Andreasson, Kaj Blennow, Ann Brinkmalm-Westman
Acta neurologica Scandinavica - 2008-01-01 -
Evaluation of sample fractionation using micro-scale liquid-phase isoelectric focusing on mass spectrometric identification and quantitation of proteins in a SILAC
experiment
Annika Thorsell, Erik Portelius, Kaj Blennow, Ann Brinkmalm-Westman
RAPID COMMUNICATIONS IN MASS SPECTROMETRY - 2007-01-01 -
Characterization of amyloid β peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass
spectrometry
Erik Portelius, Ai Jun Tran, Ulf Andreasson, Rita Persson, Gunnar Brinkmalm, Henrik Zetterberg, Kaj Blennow, Ann Brinkmalm-Westman
Journal of proteome research - 2007-01-01 -
Aspects of beta-amyloid as a biomarker for Alzheimer's
disease
Ulf Andreasson, Erik Portelius, Malin E Andersson, Kaj Blennow, Henrik Zetterberg
Biomarkers in Medicine - 2007-01-01 -
Study of stable isotope labeling with amino acids in cell culture in combination with 1DE and
2DE
Annika Dahl, Erik Portelius, Kristina Hedberg-Fogel, Kaj Blennow, Ann Brinkmalm-Westman
ASMS (American Society of Mass Spectrometry, 28 May - 1 June, 2006, Seattle, USA - 2006-01-01 -
An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal
fluid.
Erik Portelius, Henrik Zetterberg, Ulf Andreasson, Gunnar Brinkmalm, Niels Andreasen, Anders Wallin, Ann Brinkmalm-Westman, Kaj Blennow
Neuroscience letters - 2006-01-01 -
Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass
spectrometry.
Erik Portelius, Ann Brinkmalm-Westman, Henrik Zetterberg, Kaj Blennow
Journal of proteome research - 2006-01-01 -
Study of relative turnover of proteins from glioblastoma cell using differential arginine
labeling
Annika Dahl, Kristina Hedberg-Fogel, Erik Portelius, Kaj Blennow, Ann Brinkmalm-Westman
HUPO (Human Proteome Organization), 2005, Munich, Germany, 29 Aug-1 Sept - 2005-01-01