Emma Eckernäs
About Emma Eckernäs
PhD student at the Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology
PhD project
Investigating the disposition and exposure-response relationships of N,N-dimethyltryptamine in the human body aiming to optimize dosing in future clinical trials. This is mainly ahcieved using nonlinear mixed-effects modelling.
Supervisors: Michael Ashton (main supervisor), Sofia Birgersson, Lars Westberg, Daniel Röshammar
Background
- MSc in Pharmacy, University of Gothenburg, 2017
- 2 years at AstraZeneca's PT&D graduate programme
Other appointments
Vice Chair, PhD student council at the Sahlgrenska Academy
Related information
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Physiologically based biopharmaceutics modeling of regional and colon absorption in
humans
C. Tannergren, H. Jadhav, Emma Eckernäs, J. Fagerberg, P. Augustijns, E. Sjogren
European Journal of Pharmaceutics and Biopharmaceutics - 2023 -
N,N-dimethyltryptamine affects electroencephalography response in a concentration-dependent manner-A pharmacokinetic/pharmacodynamic
analysis
Emma Eckernäs, C. Timmermann, R. Carhart-Harris, D. Roshammar, Michael Ashton
Cpt-Pharmacometrics & Systems Pharmacology - 2023 -
Population pharmacokinetic/pharmacodynamic modeling of the psychedelic experience induced by N,N-dimethyltryptamine - Implications for dose
considerations
Emma Eckernäs, C. Timmermann, R. Carhart-Harris, D. Roshammar, Michael Ashton
Cts-Clinical and Translational Science - 2022 -
Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human
plasma.
Emma Eckernäs, Adam Bendrioua, Chiara Cancellerini, Christopher Timmermann, Robin Carhart-Harris, Kurt-Jürgen Hoffmann, Michael Ashton
Journal of pharmaceutical and biomedical analysis - 2022 -
Physiologically Based Biopharmaceutics Modeling of Regional and Colon Absorption in
Dogs.
Emma Eckernäs, Christer Tannergren
Molecular pharmaceutics - 2021 -
Ultra high performance liquid chromatography method development for separation of omeprazole and related substances on core-shell columns using a Quality by Design
approach.
Emma Johansson, Anders Karlsson, Jufang Wu Ludvigsson
Journal of separation science - 2020