Stephan Lange
Affiliated to research
Department of Molecular and ClinicalAbout Stephan Lange
My laboratory investigates muscle development, signaling and maintenance, by studying the biological role of sarcomeric and muscle associated proteins. I am particularly interested to decipher molecular mechanisms that play a role in the development of cardiac and skeletal muscle myopathies.
Other affiliations: Associate Professor University of California San Diego, School of Medicine 9500 Gilman Dr., BRF2 # 1243-Q, La Jolla, CA-92093, USA
Lab Website: slangelab.ucsd.edu
Full list of publications: www.ncbi.nlm.nih.gov/sites/myncbi/stephan.lange.1/bibliography/41494144/public/
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The Role of Cullin-RING Ligases in Striated Muscle Development, Function, and
Disease
J. Blondelle, A. Biju, Stephan Lange
International Journal of Molecular Sciences - 2020-01-01 -
Brain region-specific amyloid plaque-associated myelin lipid loss, APOE deposition and disruption of the myelin sheath in familial Alzheimer's disease
mice
Ibrahim Kaya, Eva Jennische, Stephan Lange, A. T. Baykal, P. Malmberg, John S. Fletcher
Journal of Neurochemistry - 2020-01-01 -
The M-band: The underestimated part of the
sarcomere
Stephan Lange, N. Pinotsis, I. Agarkova, E. Ehler
Biochimica et Biophysica Acta - Molecular Cell Research - 2020-01-01 -
Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and
serum.
Meenu Rohin Rajan, Matus Sotak, Fredrik Barrenäs, Tong Shen, Kamil Borkowski, Nicholas J. Ashton, Christina Biörserud, Tomas L Lindahl, Sofia Ramström, Michael Schöll, Per Lindahl, Oliver Fiehn, John W Newman, Rosie Perkins, Ville Wallenius, Stephan Lange, Emma Börgeson
Scientific reports - 2019-01-01 -
miR-486 is modulated by stretch and increases ventricular
growth
Stephan Lange, I. Banerjee, K. Carrion, R. Serrano, L. Habich, R. Kameny, L. Lengenfelder, N. Dalton, R. Meili, Emma Börgeson, K. Peterson, M. Ricci, J. Lincoln, M. Ghassemian, J. Fineman, J. C. del Alamo, V. Nigam
Jci Insight - 2019-01-01 -
Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle
metabolism
J. Blondelle, V. Marrocco, M. Clark, P. Desmond, S. Myers, J. Nguyen, M. Wright, S. Bremner, E. Pierantozzi, S. Ward, E. Esteve, V. Sorrentino, M. Ghassemian, Stephan Lange
Communications Biology - 2019-01-01 -
PKC and PKN in heart
disease
V. Marrocco, J. Bogomolovas, E. Ehler, C. G. dos Remedios, J. Y. Yu, C. Gao, Stephan Lange
Journal of Molecular and Cellular Cardiology - 2019-01-01 -
Cullin-3-dependent deregulation of ACTN1 represents a pathogenic mechanism in nemaline
myopathy
Jordan Blondelle, Kavya Tallapaka, Jane T. Seto, Majid Ghassemian, Madison Clark, Jenni M. Laitila, Adam Bournazos, Jeffrey D. Singer, Stephan Lange
JCI Insight - 2019-01-01