Anna Reymer
About Anna Reymer
I am an independent researcher and team leader in the group of Computational and Theoretical Biochemistry, at the department of Chemistry and Molecular biology. I obtained my PhD in Chemistry in 2012 from Chalmers University of Technology with a portfolio in computational chemistry. My research interests lie within areas of mechanisms of biological regulation and macromolecular recognition with focus on protein-DNA interactions in the context of DNA transcription and DNA replication. For further information https://reymerlab.science/
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Abnormal methylation in the NDUFA13 gene promoter of breast cancer cells breaks the cooperative DNA recognition by transcription
factors
Johanna Hörberg, Björn Hallbäck, Kevin Moreau, Anna Reymer
QRB Discovery - 2022 -
Homologous basic helix-loop-helix transcription factors induce distinct deformations of torsionally-stressed DNA: a potential transcription regulation
mechanism
Johanna Hörberg, Kevin Moreau, Anna Reymer
QRB Discovery - 2022 -
Sequence-specific dynamics of DNA response elements and their flanking sites regulate the recognition by AP-1 transcription
factors.
Johanna Hörberg, Kevin Moreau, Markus J. Tamás, Anna Reymer
Nucleic acids research - 2021 -
Rational antibody design for undruggable targets using kinetically controlled biomolecular
probes
C. L. Trkulja, O. Jungholm, M. Davidson, K. Jardemark, M. M. Marcus, J. Hagglund, A. Karlsson, R. Karlsson, J. Bruton, N. Ivarsson, S. P. Srinivasa, A. Cavallin, P. Svensson, G. D. M. Jeffries, M. N. Christakopoulou, Anna Reymer, A. Ashok, G. Willman, D. Papadia, E. Johnsson, O. Orwar
Science Advances - 2021 -
Michler's hydrol blue elucidates structural differences in prion
strains
Y. Xiao, S. Rocha, C. C. Kitts, Anna Reymer, T. Beke-Somfai, K. K. Frederick, B. Nordén
Proceedings of the National Academy of Sciences of the United States of America - 2020 -
Specifically bound BZIP transcription factors modulate DNA supercoiling
transitions
Johanna Hörberg, Anna Reymer
Scientific Reports - 2020 -
New insights on human IRE1 tetramer structures based on molecular
modeling
Antonio Carlesso, Johanna Hörberg, Anna Reymer, Leif A Eriksson
Scientific Reports - 2020 -
The ancillary N-terminal region of the yeast AP-1 transcription factor Yap8 contributes to its DNA binding
specificity.
Ewa Maciaszczyk-Dziubinska, Anna Reymer, Nallani Vijay Kumar, Wojciech Białek, Katarzyna Mizio, Markus J. Tamás, Robert Wysocki
Nucleic acids research - 2020 -
A sequence environment modulates the impact of methylation on the torsional rigidity of
DNA
Johanna Hörberg, Anna Reymer
Chemical Communications - 2018 -
Sequence-dependent response of DNA to torsional stress: a potential biological regulation
mechanism
Anna Reymer, K. Zakrzewska, R. Lavery
Nucleic Acids Research - 2018 -
Computational Chemistry and Molecular Modelling
Basics
Samuel Genheden, Anna Reymer, Patricia Saenz-Méndez, Leif A Eriksson
Computational Tools for Chemical Biology - 2017 -
Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone
H1
Jan Bednar, Isabel Garcia-Saez, Ramachandran Boopathi, Amber R. Cutter, Gabor Papai, Anna Reymer, Sajad H. Syed, Imtiaz Nisar Lone, Ognyan Tonchev, Corinne Crucifix, Hervé Menoni, Christophe Papin, Dimitrios A. Skoufias, Hitoshi Kurumizaka, Richard Lavery, Ali Hamiche, Jeffrey J. Hayes, Patrick Schultz, Dimitar Angelov, Carlo Petosa, Stefan Dimitrov
Molecular Cell - 2017 -
A stretched conformation of DNA with a biological
role?
N. Bosaeus, Anna Reymer, T. Beke-Somfai, T. Brown, M. Takahashi, P. Wittung-Stafshede, S. Rocha, B. Norden
Quarterly Reviews of Biophysics - 2017 -
ATP Hydrolysis in the RecA-DNA Filament Promotes Structural Changes at the Protein-DNA
Interface
Anna Reymer, Sándor Babik, Masayuki Takahashi, Bengt Nordén, Tamás Beke-Somfai
Biochemistry - 2015 -
Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber
diversity
Anna Reymer, K. K. Frederick, Sandra Rocha, Tamas Beke-Somfai, Catherine Kitts, S. Lindquist, Bengt Nordén
Proceedings of the National Academy of Sciences of the United States of America - 2014 -
Enhanced Cellular Uptake of Antisecretory Peptide AF-16 through Proteoglycan
Binding
Maria Matson Dzebo, Anna Reymer, Kristina Fant, Per Lincoln, Bengt Nordén, Sandra Rocha
Biochemistry - 2014 -
Initial DNA Interactions of the Binuclear Threading Intercalator Λ,Λ-[μ-bidppz(bipy)4Ru2]4+: An NMR Study with
[d(CGCGAATTCGCG)]2
Lisha Wu, Anna Reymer, Cecilia Persson, Krzysztof Kazimierczuk, Tom Brown, Per Lincoln, Bengt Nordén, Martin Billeter
Chemistry - A European Journal - 2013 -
Enantiospecific kinking of DNA by a partially intercalating metal
complex
Anna Reymer, Bengt Nordén
Chemical Communications - 2012 -
Unveiling Mechanistic Details of Macromolecular Interactions: Structural Design and Molecular Modelling of DNA-Protein Systems in Their Active
State
Anna Reymer
2012 -
Ca2+ improves organization of single-stranded DNA bases in human Rad51 filament, explaining stimulatory effect on gene
recombination
Louise Fornander, Karolin Frykholm, Anna Reymer, Axelle Renodon-Cornière, Masayuki Takahashi, Bengt Nordén
Nucleic Acids Research - 2012 -
Structure of human Rad51 protein filament from molecular modeling and site-specific linear dichroism
spectroscopy
Anna Reymer, Karolin Frykholm, K. Morimatsu, M. Takahashi, Bengt Nordén
Proceedings of the National Academy of Sciences of the United States of America - 2009 -
DNA Polymorphism as an Origin of Adenine-Thymine Tract Length-Dependent Threading Intercalation
Rate
Pär Nordell, Fredrik Westerlund, Anna Reymer, A. H. El-Sagheer, T. Brown, Bengt Nordén, Per Lincoln
Journal of the American Chemical Society - 2008