Ola Grimsholm
Affiliated to Research
Department of Rheumatology a InflammationAbout Ola Grimsholm
Short background: I defended my PhD Thesis in 2008 at Umeå University with Prof. Sture Forsgren as main supervisor and Prof. Solbritt Rantapää-Dahlqvist as co-supervisor. My Thesis described the peripheral nervous system in the inflamed joint during rheumatoid arthritis and in a mouse model therof. I did my first Post doc with Prof. Lill Mårtensson-Bopp at University of Gothenburg and that is where my interest on B cells started. Thereafter I decided to move to research on human memory B cells and I did a second Post doc in the laboratory of Dr. Rita Carsetti in Rome, Italy.
Main research focus: We focus mainly on human memory B cells in health and disease.We are running projects on primary antibody deficiencies and chronic lymphocytic leukemia. We are now about to start a project in the field of rheumatology as well on the role of memory B cells in Systemic sclerosis.
Join us! We are presently looking for Master Thesis students and a Post doc who wants to join the my lab. Please contact me for more information.
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Ectopic Germinal Centres with B and T Cells and Follicular Dendritic Cell Networks in Urethral Stricture Tissue: Possible Avenue for Immunological
Treatments
Teresa Ekerhult, Ola Grimsholm, Jenny Magnusson, C. K. Gustafsson, Ralph Peeker
European Urology Open Science - 2021-01-01 -
Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in
Autoimmunity.
Alessandro Camponeschi, Natalija Gerasimcik, Ying Wang, Timothy Fredriksson, Dongfeng Chen, Chiara Farroni, Katrin Thorarinsdottir, Louise Sjökvist Ottsjö, Alaitz Aranburu, Susanna Cardell, Rita Carsetti, Inger Gjertsson, Inga-Lill Mårtensson, Ola Grimsholm
Frontiers in immunology - 2019-01-01 -
Dysregulated miR-155 and miR-125b are related to impaired B-cell responses in down
syndrome
C. Farroni, E. Marasco, V. Marcellini, E. Giorda, D. Valentini, S. Petrini, V. D'Oria, M. Pezzullo, S. Cascioli, M. Scarsella, A. G. Ugazio, G. C. De Vincentiis, Ola Grimsholm, R. Carsetti
Frontiers in Immunology - 2018-01-01 -
Long-lived plasma cells in mice and
men
Siggeir Brynjolfsson, Linn Persson Berg, Teresa Ekerhult, Inga Rimkute, Mary Jo Wick, Inga-Lill Mårtensson, Ola Grimsholm
Frontiers in Immunology - 2018-01-01 -
Age-associated B cells expanded in autoimmune mice are memory cells sharing H-CDR3-selected
repertoires
Alaitz Aranburu, Nina Höök, Natalija Gerasimcik, Bjorn Corleis, Weicheng Ren, Alessandro Camponeschi, Hans Carlsten, Ola Grimsholm, Inga-Lill Mårtensson
European Journal of Immunology - 2018-01-01 -
B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient
patients
E. Marasco, C. Farroni, S. Cascioli, V. Marcellini, M. Scarsella, E. Giorda, E. Piano Mortari, L. Leonardi, A. Scarselli, D. Valentini, C. Cancrini, M. Duse, Ola Grimsholm, R. Carsetti
Eur J Immunol - 2017-01-01 -
CD21-/low B cells in human blood are memory
cells
Katrin Thorarinsdottir, Alessandro Camponeschi, Nicola Cavallini, Ola Grimsholm, Lennart T. H. Jacobsson, Inger Gjertsson, Lill Mårtensson-Bopp
Clinical and Experimental Immunology - 2016-01-01 -
Absence of surrogate light chain results in spontaneous autoreactive germinal centres expanding V(H)81X-expressing B
cells
Ola Grimsholm, Weicheng Ren, Angelina I Bernardi, Hai-Xia Chen, Giljun Park, Alessandro Camponeschi, Dongfeng Chen, Berglind Bergmann, Nina Höök, Sofia E M Andersson, Anneli Strömberg, Inger Gjertsson, Susanna Cardell, Ulf Yrlid, A. De Riva, Inga-Lill Mårtensson
Nature Communications - 2015-01-01 -
Surrogate light chain is required for central and peripheral B-cell tolerance and inhibits anti-DNA antibody production by marginal zone B
cells
Weicheng Ren, Ola Grimsholm, Angelina I Bernardi, Nina Höök, Anna Stern, Nicola Cavallini, Inga-Lill Mårtensson
European Journal of Immunology - 2015-01-01 -
Memory B Cells in Mouse
Models
B. Bergmann, Ola Grimsholm, Brynja Kristin Thorarinsdottir, Weicheng Ren, Pernilla Jirholt, Inger Gjertsson, Inga-Lill Mårtensson
Scandinavian Journal of Immunology - 2013-01-01 -
Uncoupling of Natural IgE Production and CD23 Surface Expression
Levels
Weicheng Ren, Kristina Lagerstedt, Ola Grimsholm, Anna Stern, Jia-Bin Sun, Yu Fang, Zou Xiang, Inga-Lill Mårtensson
Plos One - 2013-01-01 -
The pre-B cell receptor
checkpoint.
Inga-Lill Mårtensson, Nina Almqvist, Ola Grimsholm, Angelina I Bernardi
FEBS letters - 2010-01-01