Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Lingual microbiota profiles of patients with geographic tongue

Artikel i vetenskaplig tidskrift
Författare Amal Dafar
Maria Bankvall
Hülya Çevik Aras
Mats Jontell
Fei Sjöberg
Publicerad i Journal of Oral Microbiology
Volym 9
Nummer/häfte 1
ISSN 2000-2297
Publiceringsår 2017
Publicerad vid Institutionen för odontologi
Institutionen för odontologi, sektion 1
Institutionen för biomedicin, avdelningen för infektionssjukdomar
Institutionen för kliniska vetenskaper
Språk English
Länkar dx.doi.org/10.1080/20002297.2017.13...
Ämnesord Benign migratory glossitis, tongue lesions, oral mucosal lesions, oral diseases, next-generation, recurrent aphthous stomatitis, benign migratory glossitis, fissured, tongue, oral microbiota, gut microbiota, prevalence, bacterial, diversity, disease, samples, Microbiology
Ämneskategorier Oral mikrobiologi

Sammanfattning

Geographic tongue (GT) is an oral mucosal lesion that affects the tongue. The association between GT and the bacterial colonization profiles of the tongue is not clear. Lingual swabs were collected from lesion sites and healthy sites of 35 patients with GT (19 males and 16 females; M-age = 54.3 +/- 16.1 years) and 22 controls (12 males and 10 females; M-age = 56.3 +/- 15.8 years). Bacterial DNA was extracted and sequenced by next-generation sequencing. At the phylum level, Fusobacteria were significantly less abundant, while Spirochaetes were significantly more abundant in GT patients compared to controls. At the operational taxonomic units level, multivariate analysis revealed distinct clusters for the three groups based on the lingual microbiota composition. Acinetobacter and Delftia were significantly associated with GT lesion and healthy sites. However, Microbacterium, Leptospira, Methylotenera, and Lactococcus were significantly associated with GT lesion sites. Additionally, Mogibacterium and Simonsiella were significantly associated with GT healthy sites and controls. The changes in the lingual microbiota profiles of patients with GT imply a shift in the lingual bacterial ecology. However, it remains unknown if this shift is a consequence of the lesions or of factors associated with the initiation and progression of the disease.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?